Results 71 to 80 of about 117,326 (185)

Absence of mutations in exon 6 of the TARDBP gene in 207 Chinese patients with sporadic amyotrohic lateral sclerosis. [PDF]

open access: yesPLoS ONE, 2013
Mutations in the TARDBP gene, which encodes the Tar DNA binding protein, have been shown to causes of both familial amyotrophic lateral sclerosis (FALS) and sporadic ALS (SALS). Recently, several novel TARDBP exon 6 mutants have been reported in patients
Cheng-hui Ye   +9 more
doaj   +1 more source

Violence research in Northeast and Southeast Asia: main themes and directions [PDF]

open access: yes, 2011
The study analyses research on violence in the Northeast and Southeast Asia with respect to four types: political, urban, domestic and youth violence, highlighting current research themes, tendencies and gaps in violence research on and in the region ...
Hensengerth, Oliver
core   +2 more sources

Self‐Regulating Sodium‐Ion Battery Materials: From Phase Reconstruction to Functional Activation

open access: yesAdvanced Materials, EarlyView.
Self‐regulating sodium‐ion batteries hinge on programmable phase behavior in layered oxides, interphases that renew without growth, and electrolytes that steer solvation and chemistry. This review distills mechanisms into design rules that span composition, site and entropy tuning, and self‐buffering anodes, linking operando evidence to choices and ...
Hong Gao   +10 more
wiley   +1 more source

Predicting Macrophage Spatial Localization from Single‐Cell Transcriptomes to Uncover Disease Mechanisms

open access: yesAdvanced Science, EarlyView.
This study presents a machine‐learning framework entitled MERLIN that infers the microanatomical localization of macrophages from single‐cell transcriptomic data in structured organs such as the kidney and brain. Applying this method to existing datasets from models of acute kidney injury and diabetic nephropathy uncovered spatially resolved insights ...
Junping Yin   +18 more
wiley   +1 more source

A promoter polymorphism (rs17222919, -1316T/G) of ALOX5AP gene is associated with decreased risk of ischemic stroke in two independent Chinese populations. [PDF]

open access: yesPLoS ONE, 2015
No coding sequence variants of the gene encoding 5-lipoxygenase-activating protein (ALOX5AP) leading to amino acid substitutions have been identified. Therefore, variants in the ALOX5AP promoter region have received attention recently.
Yujia Fan   +8 more
doaj   +1 more source

Bacteria and Fungi Synergistically Reprogram Flavonoid Metabolites in the Pericarp of Citrus Reticulata 'Chachi' During Storage

open access: yesAdvanced Science, EarlyView.
The authors employed widely targeted metabolomics, microbial amplicon sequencing, and fermentation assays to investigate the microbiome 's influence on PCRC 's (pericarp of Citrus reticulata ' Chachi ') flavonoid profile over 0–19 years of storage. Based on the correlation analysis, solid‐state and liquid‐state fermentation, and catalytic activity ...
Jianmu Su   +10 more
wiley   +1 more source

Qing history in America: past accomplishments and present trends [PDF]

open access: yes, 1984
Fifty years ago, Chinese history hardly existed as a field of study in the United States. In 1935, there were no more than a dozen active American sinologists of whom only one or two were historians.1 Today there are over sixteen hundred members of ...
Lee, James
core  

Do roads lead to grassland degradation or restoration? A case study in Inner Mongolia, China [PDF]

open access: yes, 2011
We use satellite remote sensing data of grassland cover in Inner Mongolia, China to test whether the existence of and the size of roads in 1995 is associated with the nature of the grassland in 2000 and/or if it affects the rate of change of the ...
Deng, Xiangzheng   +4 more
core   +2 more sources

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

open access: yesAdvanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo   +40 more
wiley   +1 more source

GWAS Follow-up Study Discovers a Novel Genetic Signal on 10q21.2 for Atopic Dermatitis in Chinese Han Population

open access: yesFrontiers in Genetics, 2019
Atopic dermatitis (AD) is a common inflammatory skin disease with high heritability. Two susceptibility loci have been confirmed in our previous AD genome-wide association study (GWAS).
Xin-Ying Cai   +35 more
doaj   +1 more source

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