Results 81 to 90 of about 117,326 (185)

Genetic control and geo-climate adaptation of pod dehiscence provide novel insights into the soybean domestication and expansion [PDF]

open access: yes, 2018
Loss of pod dehiscence is a key step during soybean [Glycine max (L.) Merr.] domestication. Genome-wide association analysis for soybean shattering identified loci harboring Pdh1, NST1A and SHAT1-5.
Singh, Asheesh   +2 more
core   +3 more sources

Islam in China: Uyghurs in Crisis [PDF]

open access: yes, 2020
Islam has been in China for hundreds of years and has been the religion to ten people groups in China, including the Uyghur people group. The Uyghurs have been under China’s domain since the mid-1700s and since then have stood out among the fifty-five ...
Baez, Isabella
core   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

Sino-Tibetan languages [PDF]

open access: yes, 2010
The Sino-Tibetan (ST) language family includes the Sinitic languages (what for political reasons are known as Chinese ‘dialects’) and the 200 to 300 Tibeto-Burman (TB) languages.
LaPolla, Randy J.
core  

Thermal Plasticity is Regulated by a Key MicroRNA During Range Expansion of an Invasive Fruit Fly

open access: yesAdvanced Science, EarlyView.
Populations at the invasion front of Bactrocera dorsalis adapt through reduced phenotypic and gene expression plasticity, a phenomenon likely to be driven by genetic assimilation. We identify a key miRNA‐mediated regulatory axis, in which miR‐276b post‐transcriptionally represses thw, a conserved chitin‐binding gene critical to the cold‐tolerance ...
Yan Zhao   +5 more
wiley   +1 more source

Genetic Polymorphisms of CYP2E1, GSTP1, NQO1 and MPO and the Risk of Nasopharyngeal Carcinoma in a Han Chinese Population of Southern China

open access: yesBMC Research Notes, 2010
Background Southern China is a major area for endemic nasopharyngeal carcinoma (NPC). Genetic factors as well as environmental factors play a role in development of NPC. To investigate the roles of previously described carcinogen metabolism gene variants
Zheng Yuming   +7 more
doaj   +1 more source

Yang Liangyao's Mission of 785 to the Caliph of Baġdād: evidence of an early Sino-Arabic power alliance? [PDF]

open access: yes, 2015
The primary focus of this article is the information provided in a tomb stele (shendao zhi bei 神道之碑) of a Chinese eunuch, a certain Yang Liangyao 楊良瑤 (736–806), that will be comparatively analysed against the background of the political landscape under ...
Schottenhammer, Angela
core  

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders

open access: yesAdvanced Science, EarlyView.
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang   +22 more
wiley   +1 more source

Interactions between landscape changes and host communities can regulate echinococcus multilocularis transmission [PDF]

open access: yes, 2003
An area close to the Qinghai-Tibet plateau region and subject to intensive deforestation contains a large focus of human alveolar echinococcosis while sporadic human cases occur in the Doubs region of eastern France.
Bao, G   +10 more
core   +2 more sources

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