Results 41 to 50 of about 129,338 (307)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Australia as a Southern Hemisphere power [PDF]

open access: yes, 2013
Australia’s key economic, foreign and security relations are overwhelmingly focused to our north—in Asia, North America and Europe. But our ‘soft’ power in the realms of aid, trade, science, sport and education is increasingly manifested in the Southern ...
Benjamin Reilly, Reilly, B.
core  

Late-glacial glacier events in southernmost South America: A blend of 'northern'and 'southern' hemispheric climatic signals? [PDF]

open access: yes, 2005
This paper examines new geomorphological, chronological and modelling data on glacier fluctuations in southernmost South America in latitudes 46–55°S during the last glacial–interglacial transition. Establishing leads and lags between the
Hulton, N.R.J.   +11 more
core   +1 more source

Introduction: southern worlds, globes, and spheres [PDF]

open access: yes, 2021
This collection brings together for the first time literary studies of British colonies in nineteenth-century Australia, New Zealand, South Africa, South America, Southeast Asia, and the South Pacific Islands.
Comyn, Sarah, Fermanis, Porscha
core   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Neotropical moss floras : species common to North and South America [PDF]

open access: yes, 1995
North and South America share about 675 species that show two basic patterns, namely, those with a continuous range and those with a disjunct distribution.
Delgadillo M., Claudio
core  

Paralonchothrix gen. nov., the first record of Echimyini (Rodentia, Octodontoidea) in the late Miocene of Southern South America [PDF]

open access: yes, 2021
Echimyidae is the most widely diversified family among hystricognath rodents, both in the number of species and variety of lifestyles. In the Patagonian Subregion of southern South America, extinct echimyids related to living arboreal species (Echimyini)
Piñero García, Pedro   +3 more
core   +1 more source

Loess of southern South America

open access: yesQuaternary Science Reviews, 2003
Abstract Loess and loessoid (loess-like, reworked loess) sediments extend across the Chaco–Pampean plains and the NW mountain environments of Argentina, and in neighbouring countries (Paraguay, Brazil, Uruguay, Bolivia). Loessoid sediments are much more abundant than primary loess.
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Changes in fire regimes since the last glacial maximum: an assessment based on a global synthesis and analysis of charcoal data [PDF]

open access: yes, 2007
Fire activity has varied globally and continuously since the last glacial maximum (LGM) in response to long-term changes in global climate and shorter-term regional changes in climate, vegetation, and human land use.
Prentice, I. C.   +326 more
core   +1 more source

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