Results 51 to 60 of about 129,338 (307)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The Proceedings of the South Carolina Historical Association [PDF]
, 1985 Annually, the association publishes a journal, The Proceedings, which consists of papers presented at the annual meeting. Foreign Policy of Fear: The Example of Curt Pruefer, German Diplomat by Donald M.
South Carolina Historical Association
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Diversity and distribution patterns in high southern latitude sponges [PDF]
, 2012 Sponges play a key role in Antarctic marine benthic community structure and dynamics and are often a dominant component of many Southern Ocean benthic communities.
Downey Rachel V. +11 more
core +1 more source
Publicación Electrónica de la Asociación Paleontológica Argentina, 2015 Paleogeographic reconstructions hypothesize that during the Cretaceous, South America was split into northern and southern portions by an epeiric seaway. Although the location, extent, and duration of this ancient seaway is debated, some propose that the
Gregory P. Wilson, Nan Crystal Arens
doaj
Projected response of global runoff to El Niño-Southern oscillation
Environmental Research Letters, 2021 The El Niño-Southern Oscillation (ENSO) is a major mode of interannual climate variability and is expected to affect runoff variations at a global scale.
Thanh Le, Kyung-Ja Ha, Deg-Hyo Bae
doaj +1 more source
Rivista Italiana di Paleontologia e Stratigrafia, 2023 The sedimentological characteristics and fossil vertebrates studies are notoriously increasing in the earth sciences field, as a way to infer reliable information about the biota and the paleoenvironmental and paleoclimatic context.
Juan Manuel Robledo +5 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
The Proceedings of the South Carolina Historical Association [PDF]
, 1984 Annually, the association publishes a journal, The Proceedings, which consists of papers presented at the annual meeting. The Health of Blacks in the District of Columbia, 1860-1865 by Michael A.
South Carolina Historical Association
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Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source