Results 111 to 120 of about 2,104,489 (266)

Mutant KRAS‐m6A Epitranscriptome Axis Promotes Colorectal Cancer and is a Therapeutic Target

Advanced Science, EarlyView.
Mutant KRAS‐m6A axis promotes colorectal cancer (CRC) progression. Mutant KRAS stabilizes METTL3, leading to increased m6A‐modified BCL9L mRNA and translation of BCL9L protein. BCL9L in turn mediates TGF‐β secretion to induce differentiation of Treg and an immunosuppressive microenvironment.
Danyu Chen, Pingmei Huang, Ruizhi Tao, Fenfen Ji, Qinyao Wei, Lok Hin Ko, Lianxin Zhou, Huarong Chen, Alvin Cheung, Wei Kang, Ko Fai To, Jun Yu, Chi Chun Wong   +12 more
wiley   +1 more source

Spatial distribution and driving factors of karst rocky desertification in Southwest China based on GIS and geodetector

Open Geosciences
Rocky desertification is a pressing environmental concern in Southwest China, and it significantly impacts local living conditions and regional sustainability. Employing remote sensing on a macro scale, this study focuses on identifying and analyzing the
Wei Dengfeng, Chang Yue, Song Danni, Kuang Honghai   +3 more
doaj   +1 more source

March 2025: Southwest Climate Outlook

This item from the Southwest Climate Outlook collection is made available by Climate Assessment for the Southwest (CLIMAS) at the University of Arizona with support from the University of Arizona Libraries.
Climate Assessment for the Southwest (CLIMAS)
core  

July 2012 : Southwest Climate Outlook

, 2012
This item from the Southwest Climate Outlook collection is made available by Climate Assessment for the Southwest (CLIMAS) at the University of Arizona with support from the University of Arizona Libraries.
Climate Assessment for the Southwest (CLIMAS)
core  

Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease

Advanced Science, EarlyView.
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li, Xi Wan, Xinru Su, Zechuan Li, Yue Wang, Ying Wang, Ruofei Li, Huangzhao Wei, Jianbin Zhang, Shuai Wang   +9 more
wiley   +1 more source

August 2025: Southwest Climate Outlook

This item from the Southwest Climate Outlook collection is made available by Climate Assessment for the Southwest (CLIMAS) at the University of Arizona with support from the University of Arizona Libraries.
Climate Assessment for the Southwest (CLIMAS)
core  

August 2014: Southwest Climate Outlook

, 2014
This item from the Southwest Climate Outlook collection is made available by Climate Assessment for the Southwest (CLIMAS) at the University of Arizona with support from the University of Arizona Libraries.
Climate Assessment for the Southwest (CLIMAS)
core  

May 2021: Southwest Climate Outlook

, 2021
This item from the Southwest Climate Outlook collection is made available by Climate Assessment for the Southwest (CLIMAS) at the University of Arizona with support from the University of Arizona Libraries.
Climate Assessment for the Southwest (CLIMAS)
core  

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source

Accuracy analysis of various earthquake catalogs based on ground truth locations：Several M5 earthquakes in the southwest region of China

地震科学进展
Accurate epicenter location is crucial for assessing seismic hazards and risks, investigating seismicity, and exploring the Earth’s internal structure.
Jie Yang, Wangwang Gu, Han Zhang, Sidao Ni, Risheng Chu, Minhan Sheng, Baolong Zhang   +6 more
doaj   +1 more source