Results 131 to 140 of about 121,611 (300)
An evaluation of hair-snaring devices for small-bodied carnivores in southwest China
, 2016 Human population growth is a major threat to the biodiversity of mammals in China. Rapid development of infrastructure, pollution, and poor enforcement of environmental laws in China have altered the landscape and accelerated the extinction rates of ...
Yao, Meng +13 more
core +1 more source
Advanced Science, EarlyView.Single‐cell RNA sequencing verified the presence of the VIM+ biliary epithelial cell (BEC) in the bile ducts of NAS patients. The hypoxia/TGF‐β‐CREM‐VIM axis mediated phenotypic switch toward VIM+ BEC is validated using a hypoxia/TGF‐β‐stimulated cellular model, a rat liver transplantation model, BEC‐specific Crem conditional knockout rats, and BEC ...
Zhaoyi Wu +14 more
wiley +1 more source
Spatial variations on methane emissions from Zoige alpine wetlands of Southwest China
, 2009 This study was aimed to understand the spatial variation of CH4 emissions from alpine wetlands in Southwest China on a field-scale in two phenological seasons, namely the peak growing season and the spring thaw. Methane emission rates were measured at 30
Luo, P +6 more
core
Advanced Science, EarlyView.We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma +22 more
wiley +1 more source
, 2003 Vermander Benoît. Stevan Harrell (éd.), Perspectives on the Yi of Southwest China, 2001 Stevan Harrell, Ways of Being Ethnie in Southwest China, 2001 Erik Mueggler, The Age of Wild Ghosts, Memory, Violence and Place in Southwest China, 2001.
Vermander, Benoît
core +1 more source
, 2004 We measured nutrient distribution of Picea likiangensis (Franchet) E. Pritzel var. balfouriana trees growing in a plantation by field investigations, sample tree and plot harvest in West Sichuan, Southwest China.
Berninger, F +5 more
core
Distinctive HLA five-locus haplotypes in Southwest China and South China.
, 2015 Distinctive HLA five-locus haplotypes in Southwest China and South China.
Jian-Ping Li (213287) +41 more
core +1 more source
Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies
Advanced Science, EarlyView.In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang +4 more
wiley +1 more source
Advanced Science, EarlyView.This study proposed a unified sequence‐based framework for protein binding site prediction, which adopted a tri‐track semantic multi‐source feature fusion strategy to effectively capture diverse macromolecular interaction sites and further improved the accuracy of antibody‐antigen interaction prediction.
Dongliang Hou +8 more
wiley +1 more source
Advanced Science, EarlyView.Fangchinoline is identified as a small‐molecule DNGR‐1 modulator that enhances dendritic‐cell cross‐presentation of tumor antigens. By engaging DNGR‐1 and activating Syk–Nox2 signaling, it promotes phagosomal ROS, antigen escape, MHC‐I presentation, and CD8+ T‐cell priming, thereby strengthening antitumor immunity and sensitizing tumors to PD‐1 ...
Yuan Liao +19 more
wiley +1 more source