Results 301 to 310 of about 122,185 (331)

Financing drug development via adaptive platform trials. [PDF]

open access: yesPLoS One
Cho J   +12 more
europepmc   +1 more source

Western Diet Inhibits FUT7‐Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease

open access: yesAdvanced Science, EarlyView.
In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou   +13 more
wiley   +1 more source

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

open access: yesAdvanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li   +12 more
wiley   +1 more source

Genomics reveals multiple introductions of the seventh pandemic <i>Vibrio cholerae</i> O1 El Tor lineage into Iran since 1965. [PDF]

open access: yesMicrob Genom
Bakhshi B   +6 more
europepmc   +1 more source

Sovereign Debt Without Default Penalties [PDF]

open access: possibleSSRN Electronic Journal, 2006
Summary: We develop a theory of sovereign borrowing where default penalties are not implementable. We show that when debt is held by both domestic and foreign agents, the median voter might have an interest in serving it. Our theory has important practical implications regarding (a) the role of financial intermediaries in sovereign lending, (b) the ...
Guembel, Alexander, Sussman, Oren
openaire   +6 more sources

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