Results 121 to 130 of about 57,209 (254)
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
The New Terrorist Threat: Destruction of Western Credit Ratings [PDF]
This work describes how capital terrorists and/or adversarial nations could use Western capital markets to injure Western economies and limit international power projections.
Stephen P. Ferris, Ray Sant
doaj
Sovereign Bonds and Socially Responsible Investment [PDF]
While the literature on Socially Responsible Investment (SRI) is mainly focused on the stock market, little attention has been paid to SRI in sovereign bonds.
Bastien Drut
core
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Determinants of sovereign credit ratings: Evidence from CEE countries
The goal of this paper is investigating determinants of the sovereign credit ratings in Central and Eastern European countries (CEEC). Sovereign credit ratings are important to determine a country’s financial ability to meet its obligations.
Hrvoje Jošić, Danijel Mlinarić
doaj
Does sovereign risk have an effect on corporate rating? Case-study for emerging versus developed countries [PDF]
This paper focuses on analyzing the correlation between corporate and country rating. Is there an impact from the part of the sovereign risk towards the company financial and economical performance? Can this impact be differentiated according to emerging
Cristina Maria TRIANDAFIL +1 more
core
EU sovereign ratings lags prior and after the great recession [PDF]
Mestrado em Economia Monetária e FinanceiraEstudamos as variáveis que mais afetam a alteração dos ratings soberanos na UE para as agências de classificação de crédito Fitch e S&P.
Paineli, Grazielli Angelucci
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The Correlation of Sovereign Rating and Bonds’ Interest Rate in EU Member States
The importance of borrowing is fundamental for central public administration and it consists in sources of f nancing budget def cit and ref nanc-ing government debt.
Emilian-Constantin MIRICESCU
doaj

