Results 141 to 150 of about 783,154 (338)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The Correlation of Sovereign Rating and Bonds’ Interest Rate in EU Member States

open access: yesTransylvanian Review of Administrative Sciences, 2015
The importance of borrowing is fundamental for central public administration and it consists in sources of f nancing budget def cit and ref nanc-ing government debt.
Emilian-Constantin MIRICESCU
doaj  

Sovereign risk: An estimation model for the determinants of sovereign ratings

open access: yes, 2016
The purpose of this study is to understand the determinants of sovereign risk which is assessed by sovereign ratings. Multiple regression model was used to estimate the coefficients of related macroeconomic and qualitative factors and linear transformation method is used to identify the dependent variable based on Fitch Ratings December 2015 sovereign ...
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Liquidity, risk and the global transmission of the 2007-08 financial crisis and the 2010-2011 sovereign debt crisis [PDF]

open access: yes
The paper analyses the transmission of liquidity shocks and risk shocks to global financial markets. Using a Global VAR methodology, the findings reveal fundamental di¤erences in the transmission strength and pattern between the 2007-08 financial crisis ...
Alexander Chudik, Marcel Fratzscher
core  

PIGS or Lambs? The European Sovereign Debt Crisis and the Role of Rating Agencies [PDF]

open access: yes, 2018
This paper asks whether rating agencies played a passive role or were an active driving force during Europe's sovereign debt crisis. We address this by estimating relationships between sovereign debt ratings and macroeconomic and structural variables. We
Griesbach, Björn   +2 more
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Sovereign Bonds and Socially Responsible Investment [PDF]

open access: yes
While the literature on Socially Responsible Investment (SRI) is mainly focused on the stock market, little attention has been paid to SRI in sovereign bonds.
Bastien Drut
core  

Essays in sovereign debt and sovereign credit ratings

open access: yes, 2017
Examining Board: Professor Piero Gottardi, European University Institute (Supervisor); Professor Arpad Abraham, European University Institute; Professor Luisa Lambertini , Ecole Polytechnique Federale de Lausanne; Professor Alberto Martin , Centre de Recerca en Economia ...
openaire   +1 more source

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