Results 161 to 170 of about 783,154 (338)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Synthetic Control Method for Dutch Policy Evaluation. [PDF]
Economist (Leiden), 2023 Verheuvel N, Witteman J, Vlaanderen M.
europepmc +1 more source
The information content of Hungarian sovereign CDS spreads [PDF]
In our paper we present how the Hungarian credit default swap (CDS) market functions, and indicate its position in the global credit derivatives markets.
Lóránt Varga
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Hungarian sovereign credit risk premium in international comparison during the financial crisis [PDF]
As the CDS market has been the primary market for the price discovery of Hungarian sovereign credit risk in recent years, we can gain the most reliable information about Hungarian sovereign credit risk premia by analysing the price of Hungarian CDS ...
Lóránt Varga
core
Does competition improve sovereign credit rating quality?
Journal of international financial markets, institutions, and money, 2021 Huong Vu, Rasha Alsakka, Owain ap Gwilym
semanticscholar +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The Structural Power of the State-Finance Nexus: Systemic Delinking for the Right to Development. [PDF]
Development (Rome), 2022 Muchhala B.
europepmc +1 more source
Підвищення ефективності корпоративного управління як засіб впливу на суверенний рейтинг країни [PDF]
, 2011 Стаття аналізує роль рейтингових агентств, як інститутів щодо вирішення проблеми інформаційної асиметрії. Досліджує основні способи оцінки кредитного рейтингу.
Brychko, Maryna Mykhailivna +2 more
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