Results 211 to 220 of about 945 (260)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Analyzing global utilization and missed opportunities in debt-for-nature swaps with generative AI. [PDF]

Front Artif Intell
Tkachenko N, Frieder S, Griffiths RR, Nedopil C.   +3 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Data driven healthcare insurance system using machine learning and blockchain technologies. [PDF]

PeerJ Comput Sci
Matloob I, Khan S, Bashir B, Rukaiya R, Khan JA, Alfraihi H.   +5 more
europepmc   +1 more source

Research on the effect of multiple credit ratings from the perspective of financial regulatory systems in Chinese bond market. [PDF]

PLoS One
Zhou X, Wang H, Zhang L.
europepmc   +1 more source

Light weight blockchain with IoT devices to secure smart non-fungible tokens using hybrid secure functions. [PDF]

Sci Rep
Wei L, Liu Z.
europepmc   +1 more source

Shadow Sovereign Ratings [PDF]

Economic Premise, 2011
Sovereign ratings are a necessary condition for countries to fully access international capital. Even if the sovereign government is not issuing bonds, the sovereign rating often acts as a ceiling for the private sector and can influence its international capital market access. However, 58 developing countries are still not rated by Standard and Poors,
Canuto, Otaviano, Mohapatra, Sanket, Dilip Ratha   +2 more
openaire   +3 more sources

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Comparing Sovereign Debt Rating consistency with Sovereign AML Rating Accuracy

SSRN Electronic Journal, 2020
Many stakeholders in the global anti-money laundering (AML) space, including correspondent banks, rely upon explicit or de facto AML sovereign rating services. This reliance is similar to that reposed by fixed income investors in sovereign debt ratings.
openaire   +1 more source