Results 201 to 210 of about 690,548 (321)

Sovereign Ratings: An Analysis of the Degree, Changes and Source of Moody's Judgement

, 2018
Alvise Lennkh, Edmund Moshammer
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Sovereign risk: An estimation model for the determinants of sovereign ratings

, 2016
The purpose of this study is to understand the determinants of sovereign risk which is assessed by sovereign ratings. Multiple regression model was used to estimate the coefficients of related macroeconomic and qualitative factors and linear transformation method is used to identify the dependent variable based on Fitch Ratings December 2015 sovereign ...
openaire   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Assessing the asymmetric interrelationships between sovereign bond yields and selected potential determinants: The case of frontier WAMZ economies. [PDF]

Heliyon
Adom-Dankwa A, Atsu F, Gyamfi EN, Amewu G.   +3 more
europepmc   +1 more source

On the duration of sovereign ratings cycle phases

, 2019
L. Agnello, Vítor Castro, Ricardo M. Sousa   +2 more
semanticscholar   +1 more source

The Joint Dynamics of Sovereign Ratings and Government Bond Yields

Journal of Banking & Finance, 2018
Makram El-shagi, Gregor von Schweinitz
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Does BRRD mitigate the bank-to-sovereign risk channel? [PDF]

PLoS One
Lamers M, Present T, Soenen N, Vennet RV.   +3 more
europepmc   +1 more source

Modelling Asymmetric Sovereign Bond Yield Volatility with Univariate GARCH Models: Evidence from India

, 2023
M LB, Chakraborty S, Iyer V, N NM, Ledwani S.   +4 more
europepmc   +1 more source