Results 121 to 130 of about 150,938 (302)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Adaptive minimum symbol error rate beamforming assisted receiver for quadrature amplitude modulation systems [PDF]

open access: yes, 2006
An adaptive beamforming assisted receiver is proposed for multiple antenna aided multiuser systems that employ bandwidth efficient quadrature amplitude modulation (QAM).
Du, H.Q, Hanzo, L., Chen, S.
core  

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Improved broadband adaptive beamformer performance [PDF]

open access: yes
The protection of wireless communications links against interference is a key concern in mission critical systems. In particular low probability of interception (LPI) systems which operate below the thermal noise floor of the receiver are particularly ...
Tisdale, Neil
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A Modified Fast Approximated Power Iteration Subspace Tracking Method for Space-Time Adaptive Processing

open access: yesJournal of Electrical and Computer Engineering, 2010
We propose a subspace-tracking-based space-time adaptive processing technique for airborne radar applications. By applying a modified approximated power iteration subspace tracing algorithm, the principal subspace in which the clutter-plus-interference ...
Yang Zhiwei   +3 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Newborn EEG seizure detection using adaptive time-frequency signal processing [PDF]

open access: yes, 2006
Dysfunction in the central nervous system of the neonate is often first identified through seizures. The diffculty in detecting clinical seizures, which involves the observation of physical manifestations characteristic to newborn seizure, has placed ...
Rankine, Luke
core  

Sea Clutter Suppression for Shipborne DRM-Based Passive Radar via Carrier Domain STAP

open access: yesRemote Sensing
This paper proposes a new carrier domain approach to suppress spreading first-order sea clutter in shipborne passive radar systems using Digital Radio Mondiale (DRM) signals as illuminators.
Yijia Guo   +3 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

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