Results 101 to 110 of about 20,281,849 (282)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Journal of Electrical and Computer Engineering, 2010 We propose a subspace-tracking-based space-time adaptive processing technique for airborne radar applications. By applying a modified approximated power iteration subspace tracing algorithm, the principal subspace in which the clutter-plus-interference ...
Yang Zhiwei +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
, 2005 The Concept of Space-Time Spreading (STS) assisted, Adaptive Quadrature Amplitude Modulation (AQAM) aidedMC DS-CDMAis introduced. The AQAMmode-switching thresholds are determined using an on-line real-time Bit-Error-Ratio (BER) based learning procedure ...
Wei, H, Yang, L-L., Hanzo, L.
core +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Robust Algorithm for Adaptive Processingin Strong Space time Clutter Envirnment
工程科学与技术, 2009 :A novel Quiescent Pattern Control(QPC) approach was proposed for airborne radar weak signal detection in strong space time clutter environment. The new QPC approach imposed quadratic beampattern constraints in the adaptive processing and exploited the ...
doaj
Sea Clutter Suppression for Shipborne DRM-Based Passive Radar via Carrier Domain STAP
Remote SensingThis paper proposes a new carrier domain approach to suppress spreading first-order sea clutter in shipborne passive radar systems using Digital Radio Mondiale (DRM) signals as illuminators.
Yijia Guo +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source