Results 81 to 90 of about 1,288,009 (328)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Reduced-dimension space-time adaptive processing for airborne radar with co-prime array

open access: yesThe Journal of Engineering, 2019
Space-time adaptive processing (STAP) for airborne radar with co-prime arrays is shown to have excellent superiority compared to traditional STAP with uniform linear array radar.
Xiaoye Wang   +2 more
doaj   +1 more source

Multidimensional Low-Rank Filter based on the AU-HOSVD for MIMO STAP [PDF]

open access: yes, 2013
International audienceWe propose in this paper a new low rank filter for MIMO STAP (Multiple Input Multiple Output Space Time Adaptive Processing) based on the AU-HOSVD (Alternative Unfolding Higher Order Singular Value Decomposition). This decomposition
Boizard, Maxime   +5 more
core   +4 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Overview of Space-Time Adaptive Processing for Airborne Multiple-Input Multiple-Output Radar

open access: yesLeida xuebao, 2015
Multiple-Input Multiple-Output (MIMO) radar is an emerging radar system that is of great interest to military and academic organizations due to its advantages and extensive applications.
Wang Ting, Zhao Yong-jun, Hu Tao
doaj   +1 more source

Bollène-2002 experiment: radar quantitative precipitation estimation in the Cévennes–Vivarais region, France [PDF]

open access: yes, 2009
The Bollène-2002 Experiment was aimed at developing the use of a radar volume-scanning strategy for conducting radar rainfall estimations in the mountainous regions of France.
Andrieu, Hervé   +6 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

An Intelligent Sample Selection Method for Space-Time Adaptive Processing in Heterogeneous Environment

open access: yesIEEE Access, 2019
In the heterogeneous interference and target-rich environment, the clutter-plus-noise covariance matrix (CCM) estimate with a good match for the cell under test is significant for space–time adaptive processing.
Chongdi Duan, Yu Li, Wei Wei Wang
doaj   +1 more source

Adaptive Alternating Minimization Algorithms [PDF]

open access: yes, 2008
The classical alternating minimization (or projection) algorithm has been successful in the context of solving optimization problems over two variables. The iterative nature and simplicity of the algorithm has led to its application to many areas such as
Niesen, Urs   +2 more
core   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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