Results 21 to 30 of about 33,986 (255)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Full-space diversity and full-rate distributed space–time block codes for amplify-and-forward relaying networks

The Journal of Engineering, 2014
In this study, the authors propose a full-rate distributed space–time block code (D-STBC) that can operate on an arbitrary number of available relaying nodes which generates minimal network overhead when incorporating additional relaying nodes into ...
Mohammed-Taha O. El Astal, Brian P. Salmon, Jan Corné Olivier   +2 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Orthogonal Space-Time Block Codes in Vehicular Environments: Optimum Receiver Design and Performance Analysis

EURASIP Journal on Wireless Communications and Networking, 2009
We consider orthogonal space-time block codes (OSTBC) in vehicular environments, where the channels are nonidentically distributed. It is shown that the nonidentical channel statistics lead to nonidentical channel estimation errors, which consequently ...
He Jun, Kam PooiYuen
doaj   +2 more sources

Space-Time Block Coded Spatial Modulation

IEEE Transactions on Communications, 2011
A novel multiple-input multiple-output (MIMO) transmission scheme, called space-time block coded spatial modulation (STBC-SM), is proposed. It combines spatial modulation (SM) and space-time block coding (STBC) to take advantage of the benefits of both while avoiding their drawbacks.
Başar, Ertuğrul, Panayırcı, Erdal, Aygölü, Ümit, Panayırcı, Erdal, Poor, H. Vincent   +4 more
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Coding advantage optimization of space-time-frequency block codes [PDF]

Journal of Communications and Networks, 2020
In this article, we study the coding advantage of space-time-frequency block codes (STFBCs). Since in MIMO-OFDM coding there is the potential of exploiting space, time and frequency diversities and as the frequency tones of OFDM modulation are relatively substantial, the intricate structure of STFBCs makes it almost impossible to optimize the ...
Vahid Momenaei Kermani, Hossein Momenaee Kermani, Alireza Morsali   +2 more
openaire   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Simple scheme combining space-time coded OFDM with multi-dimension beamforming

Tongxin xuebao, 2006
A simple and efficient combining scheme was proposed for MIMO-OFDM system, which jointly designed space time block codes and multi-dimension eigen-beamforming according to second-order statistics of channels. The proposed scheme would achieve the maximum
HUANG Yong-ming, YANG Lv-xi
doaj   +2 more sources