Results 41 to 50 of about 33,986 (255)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Spatial Block Codes Based on Unitary Transformations Derived from Orthonormal Polynomial Sets

EURASIP Journal on Advances in Signal Processing, 2002
Recent work in the development of diversity transformations for wireless systems has produced a theoretical framework for space-time block codes. Such codes are beneficial in that they may be easily concatenated with interleaved trellis codes and yet ...
Mandyam Giridhar D
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Double-differential coding for orthogonal space-time block codes [PDF]

2008 IEEE International Conference on Acoustics, Speech and Signal Processing, 2008
Communications over multiple-input multiple- output (MIMO) channels with carrier offsets is an important practical and theoretical problem. Double-differential coding is a technique, which allows the receiver to decode the data without any channel or carrier offset knowledge.
Manav R. Bhatnagar, Are Hjørungnes, Lingyang Song   +2 more
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Generalized Alamouti Codes for Trading Quality of Service against Data Rate in MIMO UMTS

EURASIP Journal on Advances in Signal Processing, 2004
New space-time block coding schemes for multiple transmit and receive antennas are proposed. First, the well-known Alamouti scheme is extended to transmit antennas achieving high transmit diversity.
Rupp Markus, Mecklenbräuker Christoph F   +1 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Physical Layer Security for Multiple-Input Multiple-Output Systems by Alternating Orthogonal Space-Time Block Codes

IEEE Open Journal of the Communications Society, 2020
Algorithms are provided to build a large set of unique complex-valued orthogonal space-time block codes (STBCs) from a known or standard STBC. A physical layer security (PLS) scheme is proposed to take advantage of this set by alternating the STBC in use
Michael R. Cribbs, Ric A. Romero, Tri T. Ha   +2 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source