Results 41 to 50 of about 169,690 (256)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

KALMAN FILTERING FOR SPACE-TIME CODED TRANSMISSIONS OVER FREQUENCY-SELECTIVE RAYLEIGH FADING CHANNELS

open access: yesElectrica, 2005
The problem of multichannel estimation for space-time coded transmissions over frequency-selective Rayleigh fading channels is addressed. Under  fast fading conditions, receivers employing Kalman filtering and moderate complexity equalization schemes are
Ahmet Korhan TANÇ, Reyat YILMAZ
doaj   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Unified OSTBC-based communication scheme for cooperative space vehicles

open access: yesThe Journal of Engineering, 2019
In many spatial cooperative vehicle networks, omni-directional communication is preferred due to its flexibility for networking. In the recent studies, space time code was shown to be an effective approach for improving the performance of the omni ...
Jian Geng   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

SPACE TIME CODING FOR TRELLIS CODED MODULATION IN ADDITIVE WHITE GAUSSIAN CHANNELS

open access: yesElectrica, 2003
In this study, Trellis Coded Modulation (TCM) technique is combined with Space Time Codes (STC) and error performance is investigated in Additive White Gaussian (AWGN) channels. For this purpose a different receiver structure is proposed and mathematical
Ömer ERKAN   +2 more
doaj   +2 more sources

Transmitter diversity antenna selection techniques for wireless channels utilizing differential space-time block codes

open access: yesJournal of Telecommunications and Information Technology, 2006
The paper deals with transmitter diversity antenna selection techniques (ASTs) for wireless channels utilizing differential space-time block codes (DSTBCs).
Le Chung Tran   +3 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Space Time Codes from Permutation Codes

open access: yesCoRR, 2007
A new class of space time codes with high performance is presented. The code design utilizes tailor-made permutation codes, which are known to have large minimal distances as spherical codes. A geometric connection between spherical and space time codes has been used to translate them into the final space time codes.
openaire   +2 more sources

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