Results 61 to 70 of about 18,007,628 (277)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Space Time Codes from Permutation Codes

open access: yesCoRR, 2007
A new class of space time codes with high performance is presented. The code design utilizes tailor-made permutation codes, which are known to have large minimal distances as spherical codes. A geometric connection between spherical and space time codes has been used to translate them into the final space time codes.
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Space-time acoustic coding metasurfaces with scattering reduction characteristics

open access: yesiScience
Summary: In recent years, constructing space-time joint modulation acoustic metasurfaces with harmonic manipulation capabilities to achieve excellent scattering reduction within three-dimensional (3D) space has remained a significant challenge.
Sheng He   +5 more
doaj   +1 more source

KOMBINASI ORTHOGONAL SPACE TIME BLOCK CODING DAN BLOCK CHANNEL CODING UNTUK MENINGKATKAN KINERJA SISTEM ORTHOGONAL FREQUENCY DIVISION MULTIPLEXING

open access: yesTeknologi dan Kejuruan, 2012
It is well known that space-time diversity using space-time coding (STC) is an effective technique to improve wireless communication performance. STC was designed for flat fading channel and consist of space-time trellis code (STTC) and space-time block ...
Muladi Muladi
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Space-Time Trellis and Space-Time Block Coding Versus Adaptive Modulation and Coding Aided OFDM for Wideband Channels

open access: yes, 2006
—The achievable performance of channel coded spacetime trellis (STT) codes and space-time block (STB) codes transmitted over wideband channels is studied in the context of schemes having an effective throughput of 2 bits/symbol (BPS) and 3 BPS.
Liew, T.H., Hanzo, L.
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Distributed convolutional-coded differential space-time block coding for cooperative communications

open access: yes, 2010
A low complexity distributed coding scheme is proposed for communications over Rayleigh fading channels. Convolutional Coding (CC) assisted Differential Phase-Shift Keying (DPSK) modulation is employed at the source node for conveying the source signals ...
Wang, Yang   +5 more
core   +1 more source

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