Results 61 to 70 of about 219,853 (288)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Neutral signature gauged supergravity solutions

Journal of High Energy Physics, 2021
We classify all supersymmetric solutions of minimal D = 4 gauged supergravity with (2) signature and a positive cosmological constant which admit exactly one Killing spinor.
J. Gutowski, W. A. Sabra
doaj   +1 more source

Interacting Relativistic Particle: Time-Space Noncommutativity And Symmetries

, 2007
We discuss the symmetry properties of the reparametrization invariant model of an interacting relativistic particle where the electromagnetic field is taken as the constant background field.
Aitchison I. J. R., Balachandran A. P., Balachandran A. P., Connes A., Connes A., Dirac P. A. M., Gopakumar R., Minwalla S., R. P. MALIK, Seiberg N., Sundermeyer K., Witten E.   +11 more
core   +1 more source

On the Space-Time Symmetries of Non-Commutative Gauge Theories [PDF]

, 2001
We study the space-time symmetries and transformation properties of the non-commutative U(1) gauge theory, by using Noether charges. We carry out our analysis by keeping an open view on the possible ways $\theta^{\mu \nu}$ could transform.
A. IORIO, Jackiw R., T. SÝKORA
core   +2 more sources

Self-consistent symmetries in the proton-neutron Hartree-Fock-Bogoliubov approach [PDF]

, 2009
Symmetry properties of densities and mean fields appearing in the nuclear Density Functional Theory with pairing are studied. We consider energy functionals that depend only on local densities and their derivatives.
C. Truesdall, D. A. Varshalovich, G. Birkhoff, G. F. Bertsch, G. Ripka, G. Ripka, H. W. Turnbull, J. Dobaczewski, J. Dobaczewski, J. M. Eisenberg, L. E. Dickson, P. J. Olver, P. Ring, S. G. Kadmenskii, S. G. Rohoziński, W. Nazarewicz   +15 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Non-Lorentzian expansions of the Lorentz force and kinematical algebras

Journal of High Energy Physics
We consider non-Lorentzian expansions, Galilean and Carrollian, of the Lorentz force equation in which both the particle position and the electro-magnetic field are expanded.
José Luis V. Cerdeira, Joaquim Gomis, Axel Kleinschmidt   +2 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Non-expanding horizons: multipoles and the symmetry group

Journal of High Energy Physics, 2022
It is well-known that blackhole and cosmological horizons in equilibrium situations are well-modeled by non expanding horizons (NEHs) [1–3]. In the first part of the paper we introduce multipole moments to characterize their geometry, removing the ...
Abhay Ashtekar, Neev Khera, Maciej Kolanowski, Jerzy Lewandowski   +3 more
doaj   +1 more source

Field theories with homogenous momentum space

, 2009
We discuss the construction of a scalar field theory with momentum space given by a coset. By introducing a generalized Fourier transform, we show how the dual scalar field theory actually lives in Snyder's space-time.
Etera Livine, Florian Girelli, Jerzy Kowalski-Glikman, M. Szczachor, R. Durka   +4 more
core   +2 more sources