Results 141 to 150 of about 4,057,470 (304)

Multiwavelength Observations for a Double-decker Filament Channel in AR 13102

The Astrophysical Journal
We present the observational evidence of the existence of a double-decker filament channel (FC) by using observations in extreme ultraviolet and H α wavelengths.
Yin Zhang, Baolin Tan, Quan Wang, Jing Huang, Zhe Xu, Kanfan Ji, Xiao Yang, Jie Chen, Xianyong Bai, Zhenyong Hou, Yuanyong Deng   +10 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Evaluation of scheduling techniques for payload activity planning [PDF]

Two tasks related to payload activity planning and scheduling were performed. The first task involved making a comparison of space mission activity scheduling problems with production scheduling problems.
Bullington, Stanley F.
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

First Light for the New 30 m Parabolic Radio Telescope at ArQi: Implications for Space Weather Monitoring

The Astronomical Journal
Interplanetary scintillation (IPS) phenomenon behaves as twinkling of a compact radio source due to scattering in the solar wind. Here we report the first identification of IPS signal by a new parabolic dish antenna with its diameter of 30 m, observed on
Ming Xiong, Wei Wang, Cang Su, Jin Fan, Junhui Peng, Jun Cheng, Yanchen Gao, Man Zhang, Yongzhi Ye, Zhijun Chen, Zhichao Zhou, Sha Li, Xinhua Zhao, Liping Yang, Chengming Tan, Wenshuai Cheng, Xueshang Feng, Yihua Yan   +17 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

A Deep Learning-Enabled Ionogram Dataset for Detection and Classification of Low-latitude Spread-F Phenomena

Scientific Data
Research on the ionospheric Spread-F (SF) phenomenon holds significant value in both fields as ionospheric electrodynamic research and enhanced operational applications in radio-based technologies (e.g., communication and navigation).
Pengdong Gao, Qingyi Zhu, Jinhui Cai, Zheng Wang, Guojun Wang, Meiyi Zhan, Quan Qi, Jiankui Shi, Chu Qiu, Bo Wang, Yajun Zhu, Xiao Wang, Kai Ding   +12 more
doaj   +1 more source