Results 41 to 50 of about 5,429,621 (290)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
DC electric field distribution in planar dielectric in the presence of space charge [PDF]
, 2007 Electric field in a dielectric material under dc conditions is determined by conductivity of the material. It is well known that the dc conductivity is a function of both temperature and electric field.
Z. Xu +5 more
core +2 more sources
Space Charge in LLDPE Loaded with Nanoparticles [PDF]
, 2007 Fillers are widely used in insulation systems to achieve specific electrical, mechanical and thermal properties. Recently, polymer nanocomposites have attracted significant attention as a means of improving their performance and widening their utility ...
Steven, G, Zhang, C, Chen, G
core +2 more sources
Longitudinal space charge debunching and compensation in high-frequency accelerators
Physical Review Special Topics. Accelerators and Beams, 1999 Space charge debunching is a major issue for future high-gradient, high-frequency accelerator techniques. Space charge will set limits on the maximum six-dimensional phase space density obtainable in optical or plasma based accelerators.
L. C. Steinhauer, W. D. Kimura
doaj +1 more source
High Voltage, 2020 The Maxwell–Wagner model and bipolar charge transport model both aim at describing the charge transport behaviours in dielectrics. The Maxwell–Wagner model performs well in calculating the polarisation current and electric field distribution, but it is ...
Hucheng Liang +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Space Charge Accumulation Characteristics in HVDC Cable under Temperature Gradient
Energies, 2020 One of the main issues that affect the development of high-voltage direct-current (HVDC) cable insulation is the accumulation of space charge. The load operation of an HVDC cable leads to the formation of a radially distributed temperature gradient (TG ...
Yifan Zhou, Wei Wang, Tailong Guo
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source