Results 51 to 60 of about 5,188,114 (289)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
An improved pulsed electroacoustic system for space charge measurement under AC conditions [PDF]
, 2010 In this paper, an improved space charge measurement system based on the pulsed electro acoustic technique (PEA) is presented. The new system gives an essential way to examine the role of space charge in electrical aging process under AC conditions.
Xu, Z., Chen, G., Zhao, J.
core +2 more sources
Two particle model for studying the effects of space-charge force on strong head-tail instabilities
Physical Review Accelerators and Beams, 2016 In this paper, we present a new two particle model for studying the strong head-tail instabilities in the presence of the space-charge force. It is a simple expansion of the well-known two particle model for strong head-tail instability and is still ...
Yong Ho Chin +2 more
doaj +1 more source
Energies, 2018 Based on the existing acknowledgment that space charge modulates AC and DC breakdown of insulating materials, this investigation promotes the related investigation into the situations of more complex electrical stress, i.e., AC-DC combined voltages ...
Yuanwei Zhu +5 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
SPE Polymers, 2021 Epoxy nano Al composites were prepared using epoxyresin, hardener, and Al nanoparticles with required proportions and irradiated with gamma rays of required dosage.
Naresh Chillu +2 more
doaj +1 more source
Journal of Physics: Conference Series, 2018 The performance of the CERN Low Energy Ion Ring with electron cooled ion beams is presently limited by losses occurring once the beam has been captured in the RF buckets. An intense machine study program was started by the end of 2015 to mitigate the losses and improve the performance of the accelerator.
Saá Hernández, Angela +5 more
openaire +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
, 2006 This paper reports on the result of space charge evolution in cross-linked polyethylene (XLPE) planar samples of approximately 220 ?m thick. The space charge measurement technique used in this study is the PEA method.
Tanaka, Y +5 more
core +1 more source