Results 111 to 120 of about 3,876,747 (291)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Context-Aware Group Elevator Scheduling

open access: yes, 2006
Elevators are mobile systems where scheduling algorithms are used to assign elevator cars to passenger calls. Modern elevator-scheduling algorithms try to find an optimal assignment for an efficient and fast passengertransportation service based on ...
Strang, Thomas, Bauer, Christian
core  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Artificial Intelligence to Facilitate the Conceptual Stage of Interior Space Design: Conditional Generative Adversarial Network-Supported Long-Term Care Space Floor Plan Design of Retirement Home Buildings

open access: yesApplied Artificial Intelligence
This study uses Conditional Generative Adversarial Network (CGAN) to construct a method for generating floor plans for long-term care spaces in retirement home buildings to assist architects in improving interior space design.
Yanyu Li   +7 more
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Ventura: A Character’s Mental Landscape as History

open access: yesInternational Journal of Film and Media Arts, 2017
Pedro Costa’s last film, Cavalo Dinheiro [Horse Money, 2014], continues the work with Ventura in a way that could be seen to overtake Vanda’s role in his series of films since Ossos [Bones, 1997].
Edmundo Cordeiro
doaj  

Aging Adaptation Transition of Health Care Buildings for Accessibility Optimization for the Elderly

open access: yesBuildings
As society develops, the aging population issue is becoming more serious and gaining global attention. Meanwhile, the building industry worldwide is focusing on making buildings more convenient for the elderly.
Chang Yi   +4 more
doaj   +1 more source

Development and implementation of microcontroller-based elevator model

open access: yes, 2016
In this project, the basics of an elevator, from it's working principles to physical components were discussed. Necessary elevator components were selected, the elevator model was assembled.
Alimi, Muhammed Abdulrasheed
core  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Quick interplanetary trajectories in presence of a space elevator,

open access: yes, 2015
A space elevator is a very effective gateway to the solar system, with a potential of enabling both robotic and human exploration to be faster and cheaper.
Maffione, Porzia Federica   +1 more
core  

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