Results 101 to 110 of about 1,700,153 (295)
The use of acoustics in space exploration
, 2007 In recent years increased attention has been paid to the potential uses of acoustics forextraterrestrial exploration. The extent to which acoustics per se is used in these studiesvaries greatly. First, there are the cases in which acoustics is simply the
Leighton, T.G.
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Outer Space: The Final Frontier or the Final Battlefield? [PDF]
, 2017 Current law concerning the militarization and weaponization of outer space is inadequate for present times. The increased implementation of “dual-use” space technologies poses obstacles for the demilitarization of space. This paper examines how far the
Taft, Emily
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Geological characteristics of Chang’E-6 landing area in micro-scale unveiled by new observation data
Nature CommunicationsChang’E-6 mission successfully achieved humanity’s first sample return from the farside of the Moon. Here, we report a high-precision terrain dataset with millimeter-to-decimeter spatial resolution around the CE-6 landing site. Based on this dataset, the
Wei Yan +10 more
doaj +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Trade studies for nuclear space power systems [PDF]
As human visions of space applications expand and as we probe further out into the universe, our needs for power will also expand, and missions will evolve which are enabled by nuclear power.
Bents, David J. +2 more
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Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Halley's comet 1985-86: space exploration [PDF]
A coordinated program to explore Halley's comet in 1985 to 86 is proposed. The program employs a variety of observational systems for remote observations and utilizes spacecraft encounters with the comet to obtain in-situ measurements.
Farquhar, R. W., Wooden, W. H., II
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