Results 81 to 90 of about 5,289,200 (291)

Living Inside the UA Space Analog

Immediate accessThis item is made available by the University of Arizona Center for Human Space Exploration (CHaSE) with support from the University of Arizona Libraries.
Tresch, Trent
core   +1 more source

Descent trajectory reconstruction and landing site positioning of Chang’E-4 on the lunar farside

Nature Communications, 2019
The Chang’E-4 mission in January 2019 had the major challenge to land on the lunar far side without traditional radiometric techniques due to the missing line-of-sight.
Jianjun Liu, Xin Ren, Wei Yan, Chunlai Li, He Zhang, Yang Jia, Xingguo Zeng, Wangli Chen, Xingye Gao, Dawei Liu, Xu Tan, Xiaoxia Zhang, Tao Ni, Hongbo Zhang, Wei Zuo, Yan Su, Weibin Wen   +16 more
doaj   +1 more source

Effect of Tilted Misalignment on Tribo-Characteristics of High-Speed Ball Bearings in Liquid Hydrogen

Tribology Online, 2010
When radial load applied to the bearings was high, ball excursion occurring in the retainer ball-pockets became large due to ball-speed-variation (BSV). Such BSV was also caused by inclination of the outer race to the shaft (tilted misalignment).
Masataka Nosaka, Satoshi Takada, Makoto Yoshida, Masataka Kikuchi, Takayuki Sudo, Shohei Nakamura   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

High Altitude Skydiving Apparatus

, 2022
Immediate accessThis item is made available by the University of Arizona Center for Human Space Exploration (CHaSE) with support from the University of Arizona Libraries.
Tresch, Trent
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Impact Study of Assimilating Fengyun-3 GNSS-R Ocean Surface Winds in the Weather Research and Forecasting Model: Sensitivity Analysis on Observation Error Specifications

Remote Sensing
The Global Navigation Satellite System Reflectometry (GNSS-R) technique provides global ocean surface wind observations unaffected by rainfall with high spatiotemporal resolution.
Guanyi Wang, Weihua Bai, Feixiong Huang, Yueqiang Sun, Junming Xia, Xianyi Wang, Xiangguang Meng, Peng Hu, Cong Yin, Guangyuan Tan, Ruhan Wu, Yunlong Du, Xiaofeng Meng   +12 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Explorative Inbetweening of Time and Space

We introduce bounded generation as a generalized task to control video generation to synthesize arbitrary camera and subject motion based only on a given start and end frame. Our objective is to fully leverage the inherent generalization capability of an image-to-video model without additional training or fine-tuning of the original model.
Haiwen Feng, Zheng Ding, Zhihao Xia, Simon Niklaus, Victoria Fernández Abrevaya, Michael J. Black, Xuaner Zhang   +6 more
openaire   +3 more sources