Results 81 to 90 of about 287,012 (310)
Initial performance of the radio occultation experiment in the Venus orbiter mission Akatsuki
Earth, Planets and Space, 2017 After the arrival of Akatsuki spacecraft of Japan Aerospace Exploration Agency at Venus in December 2015, the radio occultation experiment, termed RS (Radio Science), obtained 19 vertical profiles of the Venusian atmosphere by April 2017.
Takeshi Imamura +38 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Descent trajectory reconstruction and landing site positioning of Chang’E-4 on the lunar farside
Nature Communications, 2019 The Chang’E-4 mission in January 2019 had the major challenge to land on the lunar far side without traditional radiometric techniques due to the missing line-of-sight.
Jianjun Liu +16 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Design Space Exploration of Parallel Architectures
, 2011 This chapter will present two significant applications of theMULTICUBE design space exploration framework. The first part will present the design space exploration of a low power processor developed by STMicroelectronics by using the modeFRONTIER tool ...
F. Castro +25 more
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Astrocyte heterogeneity in brain metastases
Molecular Oncology, EarlyView.Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
Remote SensingThe Global Navigation Satellite System Reflectometry (GNSS-R) technique provides global ocean surface wind observations unaffected by rainfall with high spatiotemporal resolution.
Guanyi Wang +12 more
doaj +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Solution Space Exploration in Model-Based Realization of Engineered Systems [PDF]
, 2016 With growing interest in the model-based realization of engineered systems there is a need for developing methods to explore the solution space that is defined by models that approximate reality and are typically incomplete, inaccurate with different ...
Sabeghi, Maryam
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