Results 81 to 90 of about 1,700,153 (295)
Descent trajectory reconstruction and landing site positioning of Chang’E-4 on the lunar farside
Nature Communications, 2019 The Chang’E-4 mission in January 2019 had the major challenge to land on the lunar far side without traditional radiometric techniques due to the missing line-of-sight.
Jianjun Liu +16 more
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
The idea of space exploration [PDF]
Public reactions to the space program, especially to the 1969 Moon landing are discussed. Space exploration is compared to explorations during the Age of Discovery.
Mazlish, B.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The future of space exploration and human development [PDF]
, 2008 This repository item contains a single issue of The Pardee Papers, a series papers that began publishing in 2008 by the Boston University Frederick S. Pardee Center for the Study of the Longer-Range Future.
Kalam, A.P.J. Abdul
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
A Simplified Extension of Physics-Based Single Particle Model for Dynamic Discharge Current
IEEE Access, 2019 The prediction of the battery temperature and terminal voltage under dynamic load condition is crucial for a satellite battery management system. Restricted by parameter measurability and computing resources, equivalent circuit model has been commonly ...
Jinglong Chen +3 more
doaj +1 more source
Imaging in Space Exploration [PDF]
American Journal of Neuroradiology, 2011 I remember the amazement I felt when man walked on the moon. Today, I feel that monies spent on space exploration would be better used in green energy and ocean preservation programs. We already live on earth, the most perfect spaceship of all: Why go beyond it?
openaire +2 more sources
Space exploration and world peace [PDF]
The possibility of using space exploration as an instrument in procuring world peace is studied. Suggestions for obtaining such a peace, utilizing space programs, include removal of worldwide educational and communication barriers, building of an ...
Mercieca, C.
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source