Results 61 to 70 of about 1,700,153 (295)

Design Space Exploration in Cyber-Physical Systems [PDF]

, 2019
Cyber physical systems (CPS) integrate a variety of engineering areas such as control, mechanical and computer engineering in a holistic design effort.
Amir, Maral
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Dispelling the myth of robotic efficiency: why human space exploration will tell us more about the Solar System than will robotic exploration alone

, 2012
There is a widely held view in the astronomical community that unmanned robotic space vehicles are, and will always be, more efficient explorers of planetary surfaces than astronauts (e.g. Coates, 2001; Clements 2009; Rees 2011).
Beattie, Clements, Coates, Cockell, Crawford, Crawford, Garvin, I A Crawford, Leone, Lester, NRC, Orloff, Rees, Snook, Spudis, Squyres, Turner, Wilhelms, Wilson   +18 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Improvement of Durability of Hybrid Ceramic Ball Bearings in Liquid Hydrogen at 3 Million DN (120,000 rpm)

Tribology Online, 2010
The durability of a hybrid ceramic 25-mm-bore ball bearing having a single outer land-guided retainer was evaluated and improved in liquid hydrogen at speeds up to 120,000 rpm (120,000 min-1) (3 million DN) by comparing the propagation of superficial ...
Masataka Nosaka, Satoshi Takada, Makoto Yoshida, Masataka Kikuchi, Takayuki Sudo, Shohei Nakamura   +5 more
doaj   +1 more source

Optimization of patch antennas via multithreaded simulated annealing based design exploration [PDF]

, 2017
In this paper, we present a new software framework for the optimization of the design of microstrip patch antennas. The proposed simulation and optimization framework implements a simulated annealing algorithm to perform design space exploration in order
Richie, James, Ababei, Cristinel
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Geometric Calibration of the ShadowCam Instrument on the Korea Pathfinder Lunar Orbiter

Journal of Astronomy and Space Sciences
The ShadowCam instrument on the Danuri spacecraft provides high-resolution views of shadowed portions of the Moon, which are illuminated by naturally scattered light from nearby sunlit terrain. The sensitive time-delay integration detector captures high
Emerson Jacob Speyerer, Mark Southwick Robinson, David Carl Humm, Nicholas Michael Estes, Victor Hugo Silva, Robert Vernon Wagner, Prasun Mahanti, Scott Michael Brylow   +7 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Simulation Analysis of Inverting Marine Vertical Deflection Using Spaceborne GNSS-R Interferometric Altimetry

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Global marine vertical deflection is essential for understanding Earth's internal mass and density distribution and improving the long-term inertial navigation accuracy of underwater vehicles.
Lichang Duan, Junming Xia, Weihua Bai, Zhenhe Zhai, Feixiong Huang, Cong Yin, Yueqiang Sun, Qifei Du, Dongwei Wang, Xianyi Wang, Yixuan Sun, Shengyu Kang, Guanyi Wang, Xiaofeng Meng, Yunlong Du   +14 more
doaj   +1 more source