Results 61 to 70 of about 287,012 (310)

Estimation of Mode Transition in a Supersonic Combustor

open access: yesJournal of Thermal Science and Technology, 2013
A quasi-one dimensional calculation was carried out to figure out supersonic combustor performances. Three flow tubes were considered in the combustor region. Those were an air-flow-tube, a combustion-flow-tube and a fuel-flow-tube.
Junji NODA   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Geometric Calibration of the ShadowCam Instrument on the Korea Pathfinder Lunar Orbiter

open access: yesJournal of Astronomy and Space Sciences
The ShadowCam instrument on the Danuri spacecraft provides high-resolution views of shadowed portions of the Moon, which are illuminated by naturally scattered light from nearby sunlit terrain. The sensitive time-delay integration detector captures high
Emerson Jacob Speyerer   +7 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

High Altitude Skydiving Apparatus

open access: yes, 2022
Immediate accessThis item is made available by the University of Arizona Center for Human Space Exploration (CHaSE) with support from the University of Arizona Libraries.
Tresch, Trent
core  

Simulation Analysis of Inverting Marine Vertical Deflection Using Spaceborne GNSS-R Interferometric Altimetry

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Global marine vertical deflection is essential for understanding Earth's internal mass and density distribution and improving the long-term inertial navigation accuracy of underwater vehicles.
Lichang Duan   +14 more
doaj   +1 more source

Improvement of Durability of Hybrid Ceramic Ball Bearings in Liquid Hydrogen at 3 Million DN (120,000 rpm)

open access: yesTribology Online, 2010
The durability of a hybrid ceramic 25-mm-bore ball bearing having a single outer land-guided retainer was evaluated and improved in liquid hydrogen at speeds up to 120,000 rpm (120,000 min-1) (3 million DN) by comparing the propagation of superficial ...
Masataka Nosaka   +5 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Detailed Photos of the USSR Sokol IVA Pressure Suit

open access: yes, 2022
Immediate accessThis item is made available by the University of Arizona Center for Human Space Exploration (CHaSE) with support from the University of Arizona Libraries.
Tresch, Trent
core  

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