Results 41 to 50 of about 5,105,031 (285)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A Tool for Parameter-space Explorations

open access: yesPhysics Procedia, 2014
4 pages, 5 figures, CSP 2014 ...
Yohsuke Murase   +2 more
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

SIMULATION STUDY OF THE ENERGETIC NEUTRAL ATOM (ENA) IMAGING MONITORING OF THE GEOMAGNETOSPHERE ON A LUNAR BASE

open access: yesSolar-Terrestrial Physics, 2021
Since the moon’s revolution cycle is exactly the same as its rotation cycle, we can only see the moon always facing Earth in the same direction. Based on the clean particle radiation environment of the moon, a neutral atomic telemetry base station could ...
Li Lu   +6 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Highly explosive basaltic eruptions driven by CO2 exsolution

open access: yesNature Communications, 2021
Mechanisms that drive highly explosive eruptions of low-viscosity magmas, such as at Sunset Crater volcano, remain uncertain. Here, the authors present evidence for an exsolved CO2 phase ~15 km beneath Sunset Crater that was the critical driver of rapid ...
Chelsea M. Allison   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Comparative Analysis of SWH Retrieval Between BDS-R and GPS-R Utilizing FY-3E/GNOS-II Data

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
High-precision sea surface significant wave height (SWH) data are crucial for advancing oceanic shipping and marine resource development. In this study, we conducted a comparative analysis of parameter sensitivity and accuracy in SWH retrieval between ...
Hui Yu   +12 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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