Results 51 to 60 of about 1,700,153 (295)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Earth, Planets and SpaceThe two-dimensional Grid-based Energetic Neutral Atom (GENA) imager, carried by the Queqiao-2 relay communication satellite, utilizes two narrow side-by-side multi-pixel shared collimators. In this study, a new set of response functions was developed for
Li Lu +6 more
doaj +1 more source
Simulation and Validation of Real-Time UAV-Based GNSS-R Altimetry Across Diverse Landforms
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingAccurate measurement of land surface elevation is essential for applications, such as terrain mapping, environmental monitoring, and ecological assessment.
Ziyin Xu +12 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Space exploration: The interstellar goal and Titan demonstration [PDF]
, 1982 Automated interstellar space exploration is reviewed. The Titan demonstration mission is discussed. Remote sensing and automated modeling are considered.
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Space exploration in neglect [PDF]
Brain, 1998 The present study investigated the gaze as well as the head and the eye-in-head movements of neglect patients while they were exploring their surroundings. A random configuration of letters was presented on the inner surface of a sphere that surrounded the subject, requiring free exploratory eye and head movements. The subjects were requested to search
H O, Karnath, M, Niemeier, J, Dichgans
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Estimation of Mode Transition in a Supersonic Combustor
Journal of Thermal Science and Technology, 2013 A quasi-one dimensional calculation was carried out to figure out supersonic combustor performances. Three flow tubes were considered in the combustor region. Those were an air-flow-tube, a combustion-flow-tube and a fuel-flow-tube.
Junji NODA +3 more
doaj +1 more source