Results 71 to 80 of about 1,700,153 (295)
Tribology Online, 2010 When radial load applied to the bearings was high, ball excursion occurring in the retainer ball-pockets became large due to ball-speed-variation (BSV). Such BSV was also caused by inclination of the outer race to the shaft (tilted misalignment).
Masataka Nosaka +5 more
doaj +1 more source
Developing Experimental Models for NASA Missions with ASSL
, 2010 NASA's new age of space exploration augurs great promise for deep space exploration missions whereby spacecraft should be independent, autonomous, and smart.
Hinchey, Mike, Vassev, Emil
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploring Protein Fold Space [PDF]
Biomolecules, 2020 The model of protein folding proposed by Ptitsyn and colleagues involves the accretion of secondary structures around a nucleus. As developed by Efimov, this model also provides a useful way to view the relationships among structures. Although somewhat eclipsed by later databases based on the pairwise comparison of structures, Efimov’s approach ...
openaire +3 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
A Probabilistic STA-Bayesian Algorithm for GNSS-R Retrieval of Arctic Soil Freeze–Thaw States
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingSoil freeze–thaw (F/T) states are a key indicator of the Arctic climate, highlighting the need for their accurate retrieval. Global navigation satellite system-reflectometry (GNSS-R) offers a promising approach for retrieving soil F/T states, as F/
Xiaofeng Meng +10 more
doaj +1 more source
Initial performance of the radio occultation experiment in the Venus orbiter mission Akatsuki
Earth, Planets and Space, 2017 After the arrival of Akatsuki spacecraft of Japan Aerospace Exploration Agency at Venus in December 2015, the radio occultation experiment, termed RS (Radio Science), obtained 19 vertical profiles of the Venusian atmosphere by April 2017.
Takeshi Imamura +38 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
AerospaceAs a cost-effective and versatile solution, small satellites are increasingly being considered for space exploration. However, one of the major challenges in deploying small satellites for high total impulse missions, particularly deep space exploration,
Yubin Zhong +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source