Results 31 to 40 of about 5,105,031 (285)

Scarcity of scale-free topology is universal across biochemical networks

open access: yesScientific Reports, 2021
Biochemical reactions underlie the functioning of all life. Like many examples of biology or technology, the complex set of interactions among molecules within cells and ecosystems poses a challenge for quantification within simple mathematical objects ...
Harrison B. Smith   +2 more
doaj   +1 more source

A New Time Series Similarity Measurement Method Based on the Morphological Pattern and Symbolic Aggregate Approximation

open access: yesIEEE Access, 2019
Aiming at the problem that the traditional similarity measurement methods cannot effectively measure the similarity of the time series with the difference both in the trend and detail, this paper proposes a new time series similarity measurement method ...
Jiancheng Yin   +5 more
doaj   +1 more source

Spectral interpretation of late-stage mare basalt mineralogy unveiled by Chang’E-5 samples

open access: yesNature Communications, 2022
Laboratory spectroscopic and X-ray diffraction analyses on the Chang’E-5 lunar soil samples have demonstrated that the spectral features of lunar late-stage mare basalts are representative of iron-rich high-Ca pyroxene rather than olivine.
Dawei Liu   +12 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Exploring the Virtual Space of Academia [PDF]

open access: yes, 2012
The aim of this chapter is to provide a view on how researchers present themselves in a social network specifically developed for supporting academic practices, how they share information and engage in dialogues with colleagues worldwide. We analysed data from 30,428 users who have registered on a publicly available website to study the effect of ...
Menendez Blanco, Maria   +2 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Submersible Space Training Suit Preliminary Test Results and Review

open access: yes
Immediate accessThis item is made available by the University of Arizona Center for Human Space Exploration (CHaSE) with support from the University of Arizona Libraries.
Smith, Cameron, Tresch, Trent
core   +4 more sources

Decreasing extents of Archean serpentinization contributed to the rise of an oxidized atmosphere

open access: yesNature Communications, 2021
Throughout the Archean, H2 generation via low-temperature ultramafic serpentinization likely helped prevent atmospheric O2 accumulation and continued until the abundance of ultramafic rocks diminished setting the stage for the Great Oxidation Event.
James Andrew M. Leong   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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