Results 31 to 40 of about 287,012 (310)
Decreasing extents of Archean serpentinization contributed to the rise of an oxidized atmosphere
Throughout the Archean, H2 generation via low-temperature ultramafic serpentinization likely helped prevent atmospheric O2 accumulation and continued until the abundance of ultramafic rocks diminished setting the stage for the Great Oxidation Event.
James Andrew M. Leong +2 more
doaj +1 more source
Exploring the Virtual Space of Academia [PDF]
The aim of this chapter is to provide a view on how researchers present themselves in a social network specifically developed for supporting academic practices, how they share information and engage in dialogues with colleagues worldwide. We analysed data from 30,428 users who have registered on a publicly available website to study the effect of ...
Menendez Blanco, Maria +2 more
openaire +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Since the moon’s revolution cycle is exactly the same as its rotation cycle, we can only see the moon always facing Earth in the same direction. Based on the clean particle radiation environment of the moon, a neutral atomic telemetry base station could ...
Li Lu +6 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Highly explosive basaltic eruptions driven by CO2 exsolution
Mechanisms that drive highly explosive eruptions of low-viscosity magmas, such as at Sunset Crater volcano, remain uncertain. Here, the authors present evidence for an exsolved CO2 phase ~15 km beneath Sunset Crater that was the critical driver of rapid ...
Chelsea M. Allison +2 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

