Results 31 to 40 of about 5,289,200 (291)
IEEE Access, 2019 Aiming at the problem that the traditional similarity measurement methods cannot effectively measure the similarity of the time series with the difference both in the trend and detail, this paper proposes a new time series similarity measurement method ...
Jiancheng Yin +5 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Decreasing extents of Archean serpentinization contributed to the rise of an oxidized atmosphere
Nature Communications, 2021 Throughout the Archean, H2 generation via low-temperature ultramafic serpentinization likely helped prevent atmospheric O2 accumulation and continued until the abundance of ultramafic rocks diminished setting the stage for the Great Oxidation Event.
James Andrew M. Leong +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Spectral interpretation of late-stage mare basalt mineralogy unveiled by Chang’E-5 samples
Nature Communications, 2022 Laboratory spectroscopic and X-ray diffraction analyses on the Chang’E-5 lunar soil samples have demonstrated that the spectral features of lunar late-stage mare basalts are representative of iron-rich high-Ca pyroxene rather than olivine.
Dawei Liu +12 more
doaj +1 more source
Exploring the Virtual Space of Academia [PDF]
, 2012 The aim of this chapter is to provide a view on how researchers present themselves in a social network specifically developed for supporting academic practices, how they share information and engage in dialogues with colleagues worldwide. We analysed data from 30,428 users who have registered on a publicly available website to study the effect of ...
Menendez Blanco, Maria +2 more
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source