Results 211 to 220 of about 1,638,848 (302)

Leveraging AlphaFold2 structural space exploration for generating drug target structures in structure-based virtual screening. [PDF]

Biochem Biophys Rep
Uchikawa K, Furui K, Ohue M.
europepmc   +1 more source

Erratum: Beyond task-space exploration: On the role of variance for motor control and learning. [PDF]

Front Psychol, 2023
Frontiers Production Office.
europepmc   +1 more source

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

Advanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali, Mohamed H. Sherif, Nashwa Barakat, Bassant Yahia, Ahmed A. Shokeir, Basel Sitohy   +5 more
wiley   +1 more source

The physiology of plants in the context of space exploration. [PDF]

Commun Biol
Maffei ME, Balestrini R, Costantino P, Lanfranco L, Morgante M, Battistelli A, Del Bianco M.   +6 more
europepmc   +1 more source

Musculoskeletal research in human space flight - unmet needs for the success of crewed deep space exploration. [PDF]

NPJ Microgravity, 2023
Liphardt AM, Fernandez-Gonzalo R, Albracht K, Rittweger J, Vico L.   +4 more
europepmc   +1 more source

Infrared Neural Stimulation Elicits Distinct Molecular Pathways in Astrocytes Based on Laser Pulse Parameters

Advanced Biology, EarlyView.
Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams, Ana I Borrachero‐Conejo, Pratheepa Kumari Rasiah, Emanuela Saracino, Roberto Zamboni, Eric Duco Jansen, Valentina Benfenati, Anita Mahadevan‐Jansen   +7 more
wiley   +1 more source

Parallel synthesis of 5'-amino-5'-deoxy-adenosine derivatives for focused chemical space exploration and their application as methyltransferase inhibitors. [PDF]

RSC Med Chem
Hoba SN, Schwickert M, Kammerer L, Sabin M, Weldert AC, Nidoieva Z, Meidner JL, Barthels F, Schirmeister T, Kersten C.   +9 more
europepmc   +1 more source

Towards sustainable human space exploration-priorities for radiation research to quantify and mitigate radiation risks. [PDF]

NPJ Microgravity, 2023
Fogtman A, Baatout S, Baselet B, Berger T, Hellweg CE, Jiggens P, La Tessa C, Narici L, Nieminen P, Sabatier L, Santin G, Schneider U, Straube U, Tabury K, Tinganelli W, Walsh L, Durante M.   +16 more
europepmc   +1 more source

Unrolling of Syngonium podophyllum: Functional Anatomy, Morphology and Modelling of Its Peltate Leaves

Advanced Biology, EarlyView.
The unrolling of the peltate leaves in Syngonium podophyllum is analyzed and quantified (left‐hand side to center). These measurements serve to verify a mathematical model for leaf unrolling based on the model used in Schmidt (2007). An additional formula for obtaining a layer mismatch from a prescribed radius is derived.
Michelle Modert, Nick Seinsche, Sören Bartels, Tom Masselter, Thomas Speck   +4 more
wiley   +1 more source

The utility of animal models to inform the next generation of human space exploration. [PDF]

NPJ Microgravity
Duporge I, Pereira T, de Obeso SC, Ross JGB, J Lee S, G Hindle A.   +5 more
europepmc   +1 more source