Cerebello‐Prefrontal Connectivity Underlying Cognitive Dysfunction in Spinocerebellar Ataxia Type 2
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 2 (SCA2) is a hereditary cerebellar degenerative disorder, with motor and cognitive symptoms. The constellation of cognitive symptoms due to cerebellar degeneration is named cerebellar cognitive affective syndrome (CCAS), which has increasingly been recognized to profoundly impact patients' quality of life;
Ami Kumar +7 more
wiley +1 more source
Magicmol: a light-weighted pipeline for drug-like molecule evolution and quick chemical space exploration. [PDF]
BMC Bioinformatics, 2023 Chen L, Shen Q, Lou J.
europepmc +1 more source
Design space exploration algorithm for heterogeneous multi-processor embedded system design [PDF]
, 2002 I. Karkowski, H. Corporaal
openalex +1 more source
Abnormal Synchronization Between Cortical Delta Power and Ripples in Hippocampal Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Discriminating between epileptogenic and physiological ripples in the hippocampus is important for identifying epileptogenic (EP) zones; however, distinguishing these ripples on the basis of their waveforms is difficult. We hypothesized that the nocturnal synchronization of hippocampal ripples and cortical delta power could be used ...
Takamitsu Iwata +10 more
wiley +1 more source
From Protosolar Space to Space Exploration: The Role of Graphene in Space Technology and Economy. [PDF]
Nanomaterials (Basel), 2023 Scalia T, Bonventre L, Terranova ML.
europepmc +1 more source
Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose (MAD) administration.
Andreas Meier +8 more
wiley +1 more source
Design Space Exploration of Clustered Sparsely Connected MPSoC Platforms. [PDF]
Sensors (Basel), 2022 Frid N, Sruk V, Jakobović D.
europepmc +1 more source
Explorations in Hubble Space: A Quantitative Tuning Fork
, 2000 Roberto Abraham, M. R. Merrifield
openalex +1 more source
Universal Proteomic Signature After Exercise‐Induced Muscle Injury in Muscular Dystrophies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Several neuromuscular disorders (NMDs) are characterized by progressive muscle damage and are marked by the elevation of circulating muscle proteins from activity‐related injury. Despite a diverse array of genetic drivers, many NMDs share similar patterns of exercise intolerance and higher concentrations of muscle injury proteins ...
Mads G. Stemmerik +5 more
wiley +1 more source
Enabling Human Space Exploration Missions Through Progressively Earth Independent Medical Operations (EIMO). [PDF]
IEEE Open J Eng Med Biol, 2023 Levin DR +6 more
europepmc +1 more source