Results 41 to 50 of about 1,601 (250)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Clinical evaluation of Fiber Reinforced Composite resin(FRC) as a space maintainer [PDF]

open access: yesIranian Journal of Orthodontics, 2007
Aim: The premature loss of primary molars and the failure to protect this site during normal growth and developmental events may put the normal occurrence of occlusion at risk in the permanent dentition.
Bahman Seraj   +2 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Assessing the Awareness of Parents and Satisfaction of Children with Intraoral Space Maintainers

open access: yesJournal of Islamic Dental Association of Iran, 2019
Background and Aim: Space maintenance is an important process in the mixed dentition as a preventive measure for multiple malocclusion problems related to the loss of arch length. The awareness of parents and the satisfaction of children are two critical
Hoda Shamsaddin   +4 more
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The negative impact of missing primary teeth with the importance of space maintainer among children attending the college of dentistry, hawler medical university in Erbil: Iraq.

open access: yesErbil Dental Journal, 2022
Background and Objectives: Premature tooth loss can cause undesirable tooth movement, resulting in space loss in the permanent teeth. The space maintainer is a tool-based procedure that is used in both preventive and corrective orthodontics.
Hozan Farid Tawfiq, Alaa Mahmud Mustafa
doaj  

MODIFIED APPROACH TO ENSURE A UNIFORM LAYER OF ELASTIC MATERIAL FOR RELINING COMPLETE DENTURES WITH SELF CURING SILICONES [PDF]

open access: yesJournal of IMAB, 2019
Setting the Problem: In the available literature, the preparation of the removable denture for the relining procedure is subjective. It is not possible to ensure a uniform thickness of the relining material in all zones, with the risk of unwanted ...
Mariana Yankova   +3 more
doaj   +1 more source

DIGITAL SPACE MAINTAINERS

open access: yesInternational Journal of Advanced Research
3D printing is a manufacturing process in which formation of an object is done by building it layer by layer. Many new developments have occurred in paediatric dentistry in recent years. As the world is advancing technologically day by day, 3-D printing technology will be the need of the hour in coming days.
Apurva Chadha   +5 more
openaire   +1 more source

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