Results 51 to 60 of about 1,601 (250)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Need of space maintainer in 5 to 7 years-old schoolchildren.

open access: yesJournal of Oral Research, 2012
Introduction: Tooth caries is the most common cause of the early loss of deciduous teeth. To avoid undesirable movement, it is often necessary to implement a space maintainer.
Patricia Alvear   +3 more
doaj   +1 more source

Space Maintainer: A Review

open access: yesIndian Journal of Forensic Medicine & Toxicology, 2020
Space maintainers are useful incases of deciduous teeth to protect the dentition from malposition,impaction,crowding,etc. They can also be used inmixeddentition. Various types of space maintainersare there forParticular treatment. This is mainly aimed atthe management of space in children.
openaire   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Anterior Space Maintainer Incorporating a Pontic Derived from a Strip Crown [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Various designs of functional and aesthetic space maintainers have been used in the anterior region to replace missing upper primary anteriors. All of these had utilised pontics made of composite, acrylic or natural teeth.
Paul Chalakkal   +3 more
doaj   +1 more source

SPACE CONTROL IN MIXED DENTITION - SPACE MAINTAINERS

open access: yesJurnalul Pediatrului, 2020
Maintaining the child's oral cavity in optimal health by preserving the morpho-functional integrity of primary teeth, given the influence they have on the growth and development of the stomatognathic system is the duty and responsibility of the pedodontist. In addition to prevention, increased attention should be granted to the space control in case of
Magda-Mihaela Luca   +6 more
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

NiTi bonded space regainer/maintainer

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2010
Early orthodontic interventions are often initiated in the developing dentition to promote favorable developmental changes. Interceptive orthodontic can eliminate or reduce the severity of a developing malocclusion, the complexity of orthodontic treatment, overall treatment time and cost. Premature loss of deciduous tooth or teeth can often destroy the
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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