Results 91 to 100 of about 173,638,451 (255)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

A Certain Class of Analytic Functions Associated with Fractional Derivative Operators

open access: yes, 2016
[[abstract]]The present paper aims at a systematic investigation of a new class S;;(; ; A;B;m) of analytic functions in open unit disk U: We have derived several results like characterization property, distortion theorem and other interesting properties ...
Sayali S. Joshi
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A weighted limit theorem in the space of analytic functions for general dirichlet series. [PDF]

open access: yes, 2014
Work reminds existing results and proves a weighted limit theorem in the space of analytic functions for general Dirichlet ...
Pacevičius, Zigmas,
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

A semi-analytical x-space solution for parton evolution — Application to non-singlet and singlet DGLAP equation

open access: yesJournal of High Energy Physics
We present a novel semi-analytical method for parton evolution. It is based on constructing a family of analytic functions spanning x-space which is closed under the considered evolution equation.
Juliane Haug   +2 more
doaj   +1 more source

On Bloch-Type Functions with Hadamard Gaps

open access: yesAbstract and Applied Analysis, 2007
We give some sufficient and necessary conditions for an analytic function f on the unit ball B with Hadamard gaps, that is, for f(z)=∑k=1∞Pnk(z) (the homogeneous polynomial expansion of f) satisfying nk+1/nk≥λ>1 for all k∈ℕ, to belong to the space ℬpα(B)=
Stevo Stevic
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Nevanlinna analytic continuation for Migdal–Eliashberg theory

open access: yesComputational Materials Today
In this work, we present a method to reconstruct real-frequency properties from analytically continued causal Green’s functions within the framework of Migdal–Eliashberg (ME) theory for superconductivity.
D.M. Khodachenko   +4 more
doaj   +1 more source

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