Results 81 to 90 of about 166,276,517 (302)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Subclasses of Analytic Functions Defined by Carlson - Shaffer Linear Operator

open access: yes, 2015
[[abstract]]We introduce the subclass LT (a, c; , ) of analytic functions with negative coefficients defined by the linear operator L(a, c)f(z) which introduced and studied by Carlson and Shaffer [4].
B. A. Frasin
core  

Cyclicity of the adjoint of weighted composition operators on the Hilbert space of analytic functions [PDF]

open access: yes, 2011
summary:In this paper, we discuss the hypercyclicity, supercyclicity and cyclicity of the adjoint of a weighted composition operator on a Hilbert space of analytic ...
Hedayatian, Karim   +2 more
core   +1 more source

A study of analytic functions along with Poisson distribution

open access: yesApplied Mathematics in Science and Engineering
In this paper, we introduce some new families of analytic functions by using Hadamard product while keeping conic like domains in view. Like the area theorem, we determine sufficient conditions as well as characterizations of these functions. Furthermore,
Muhammad Ashfaq   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Deformations of functions and F-manifolds [PDF]

open access: yes, 2004
We study deformations of functions on isolated singularities. A unified proof of the equality of Milnor and Tjurina numbers for functions on isolated complete intersections singularities and space curves is given.
De Gregorio, Ignacio   +1 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Normal and self-adjoint composition operators on the space of analytic functions

open access: yesKarpatsʹkì Matematičnì Publìkacìï, 2009
We consider spectral properties of normal composition operators and investigate some properties of self-adjoint operators on space of analytic functions on Hilbert space.
Z. G. Mozhyrovska
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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