Results 51 to 60 of about 173,638,451 (255)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Joint Approximation of Analytic Functions by Shifts of Hurwitz Zeta-Functions in Short Intervals
AxiomsFor j=1,…,r, αj∈(0,1) are such that the set {log(m+αj):m∈N0,j=1,…,r} is linearly independent over Q. In the paper, we consider simultaneous approximation of a tuple of analytic functions by shifts (ζ(s+iτ,α1),…,ζ(s+iτ,αr)) of the Hurwitz zeta-functions ...
Antanas Laurinčikas
doaj +1 more source
Composition Operators and Multiplication Operators on Weighted Spaces of Analytic Functions
International Journal of Mathematics and Mathematical Sciences, 2007 Let V be an arbitrary system of weights on an open connected subset G of ℂN(N≥1) and let B(E) be the Banach algebra of all bounded linear operators on a Banach space E.
J. S. Manhas
doaj +1 more source
On discrete universality of composite functions
Mathematical Modelling and Analysis, 2012 In 1975, S.M. Voronin proved that the Riemann zeta-function ζ (s) is universal in the sense that its shifts approximate uniformly on some sets any analytic function. Let h be a fixed positive number such that exp is irrational for all .
Jovita Rašytė
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
On a product-type operator between Hardy and α-Bloch spaces of the upper half-plane
Journal of Inequalities and Applications, 2018 Recently we have introduced a product-type operator and studied it on some spaces of analytic functions on the unit disc. Here we start investigating the operator on the space of analytic functions on the upper half-plane. We characterize the boundedness
Stevo Stević, Ajay K. Sharma
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Interpolating function and Stokes phenomena
Nuclear Physics B, 2015 When we have two expansions of physical quantity around two different points in parameter space, we can usually construct a family of functions, which interpolates the both expansions.
Masazumi Honda, Dileep P. Jatkar
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source