Results 61 to 70 of about 8,248,093 (374)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Reflective nonlinear optical limiter design based on coupled Tamm plasmon polaritons and optical Kerr effect

Results in Physics
With the increasing applications of high-power lasers in fields such as laser fabrication, laser measurement, laser therapy and scientific research, there is an increasing demand for high-performance nonlinear optical limiters (NOLs) to protect human ...
Jian Huang, Yuangang Lu, Biao Dong, Yang Liu, Chongjun He   +4 more
doaj   +1 more source

Topic Grids for Homogeneous Data Visualization

, 2016
We propose the topic grids to detect anomaly and analyze the behavior based on the access log content. Content-based behavioral risk is quantified in the high dimensional space where the topics are generated from the log.
Huynh, Jean-Laurent, Su, Shih-Chieh, Vaughn, Joseph   +2 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Understanding the Nature of Oneness Experience in Meditators Using Collective Intelligence Methods

Frontiers in Psychology, 2020
Research on meditation and mindfulness practice has flourished in recent years. While much of this research has focused on well-being outcomes associated with mindfulness practice, less research has focused on how perception of self may change as a ...
Eric Van Lente, Michael J. Hogan
doaj   +1 more source

Similarities in face and voice cerebral processing [PDF]

, 2017
In this short paper I illustrate by a few selected examples several compelling similarities in the functional organization of face and voice cerebral processing: (1) Presence of cortical areas selective to face or voice stimuli, also observed in non ...
Belin, Pascal
core   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Terrestrial health applications of visual assessment technology and machine learning in spaceflight associated neuro-ocular syndrome

npj Microgravity, 2022
The neuro-ocular effects of long-duration spaceflight have been termed Spaceflight Associated Neuro-Ocular Syndrome (SANS) and are a potential challenge for future, human space exploration.
Joshua Ong, Alireza Tavakkoli, Nasif Zaman, Sharif Amit Kamran, Ethan Waisberg, Nikhil Gautam, Andrew G. Lee   +6 more
doaj   +1 more source

"Sitting too close to the screen can be bad for your ears": A study of audio-visual location discrepancy detection under different visual projections [PDF]

, 2001
In this work, we look at the perception of event locality under conditions of disparate audio and visual cues. We address an aspect of the so called “ventriloquism effect” relevant for multi-media designers; namely, how auditory perception of event ...
Brewster, S.A., Walker, A.
core   +1 more source