Results 191 to 200 of about 4,095,835 (253)

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

Advanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger, Min Jiang, Florian Belger, Fabian Link, Benjamin Winkeljann, Olivia M. Merkel   +5 more
wiley   +1 more source

Energetic electron populations effect on HF wave propagation in plasmas and modes driven by temperature anisotropy. [PDF]

Sci Rep
Barzegar S.
europepmc   +1 more source

Microfluidic Architecting of Patchy MXene Core‐Shell Particles for Ultralow‐Loading Photothermal Shape‐Memory Actuation

Advanced Functional Materials, EarlyView.
Spatially distributing Ti3C2Tx nanosheets into core‐shell architecture, rather than as directly dispersed flakes, mitigates aggregation and enhances photon harvesting. When the Ti3C2Tx core‐shell particles are incorporated into a shape‐memory polymer matrix at an ultralow loading of 0.0024 wt%, the improved photothermal conversion translates into ...
May Maung Zaw, Maxim M. Trubyanov, Qian Wang, Siyu Chen, Hongyi Chen, Keyu Chen, Hongbin Sun, Muthu Vignesh Vellayappan, Xiaoying Qi, Sharon Mui Ling Nai, Kostya S. Novoselov, David W. Rosen, Daria V. Andreeva   +12 more
wiley   +1 more source

Particle monitor probe: a novel tool for fast plasma diagnostics and space charge compensation investigation in high-intensity proton accelerators. [PDF]

Sci Rep
Priyadarshini P, Mathew JV, Kumar R.
europepmc   +1 more source

Selenium‐Integrated Cyanine Dye With Enhanced Photophysical Properties for Optoacoustic‐Guided Cancer Imaging and Therapy

Advanced Functional Materials, EarlyView.
This study introduces selenium‐integrated cyanine dye (Se‐Cyn), with superior photostability, absorption, and photothermal efficiency, outperforming ICG in NIR window. Its nanoparticle form remains stable in water, accumulates in tumors, and enables strong optoacoustic imaging and effective phototherapy outcomes.
Divyesh Shelar, Snehal Salunkhe, Tony Fröhlich, Uwe Klemm, Pia Anzenhofer, Birgit Rathkolb, Martin Hrabě de Angelis, Oliver Plettenburg, Michael Sattler, Sudesh T. Manjare, Vipul Gujrati, Vasilis Ntziachristos   +11 more
wiley   +1 more source

Two-Temperature and Thermal Plasma Kinetic Theories. [PDF]

Entropy (Basel)
Giovangigli V.
europepmc   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Shock-induced magnetic reconnection in the Venusian magnetotail. [PDF]

Nat Commun
Zhang M, Dang T, Lei J, Zhang B, Wang R, Xiao S, Zhang T, Chen J, Yan M.   +8 more
europepmc   +1 more source

Prostate Cancer Patient‐Derived Organoids (PDOs) as Functional Avatars for Antisense Oligonucleotide (ASO)‐Based Personalized Therapy

Advanced Healthcare Materials, EarlyView.
Prostate patient‐derived organoids (PDOs) were established from TURP and biopsy specimens with >90% success and retain key features of their tissues of origin, making them functional avatars for antisense oligonucleotide (ASO) therapy . Transfecting single cells outside the Matrigel matrix and then reconstituting organoids overcomes the 3D delivery ...
Thi Thom Tran, Thi Tu Uyen Phan, Michael Baboudjian, Quang Hieu Duong, Ines Sousa, Thi Thuy Le, Virginie Baylot, Sophie Giusiano, Laurent Daniel, Pauline Brige, Benjamin Guillet, Cyrille Bastide, Carmen Garrido, David Taïeb, Thi Khanh Le, Palma Rocchi   +15 more
wiley   +1 more source

Modelling the impact of energetic electrons on electron-acoustic instabilities and HF/UHF wave propagation in the ionospheric-like plasmas. [PDF]

Sci Rep
Ebadi D, Barzegar S.
europepmc   +1 more source