Results 161 to 170 of about 13,923,765 (402)
Geometry from Information Geometry
We use the method of maximum entropy to model physical space as a curved statistical manifold. It is then natural to use information geometry to explain the geometry of space.
Caticha, Ariel
core +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
STABLE CONFIGURATION UNDER LOCAL MAJORITY TRANSFORMATIONS ON CELL SPACE : INFORMATION SCIENCE APPROACH TO BIOMATHEMATICS, V [PDF]
Masako Yamaguchi
openalex +1 more source
A research in support of NASA's space science [PDF]
An ion drift meter, extreme ultraviolet spectrometers, an extreme ultraviolet grating photometer, and a soft particle spectrometer were ...
Johnson, F. S.
core +1 more source
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková+14 more
wiley +1 more source
UVSat: a concept of an ultraviolet/optical photometric satellite
Time-series photometry from space in the ultraviolet can be presently done with only a few platforms, none of which is able to provide wide-field long-term high-cadence photometry.
Baran, A.+27 more
core
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Editorial: Applications of statistical methods and machine learning in the space sciences
Bala Poduval+4 more
doaj +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source