Results 151 to 160 of about 31,547,886 (300)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Symposium of the Arizona-Nevada Academy of Science (1973)
, 1973 SEVENTEENTH ANNUAL MEETING / May 5, 1973 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / University of Arizona / Tucson, ArizonaThis volume is part of the Arizona-Nevada Academy of Science ...
Arizona-Nevada Academy of Science
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Self-positioning in space science communication: A corpus-assisted discourse study. [PDF]
PLoS OneChen F, Ngai CSB, Liu M.
europepmc +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Towards a science-led One ESA: developing long-term prospects for science and technology
, 2013 In 2007, the ESA Director General created the High-level Science Policy Advisory Committee (HISPAC) and challenged it to address the issue of promoting and advising on the creation of a Science-led One ESA.
European Space Agency
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Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Review on space science research in Malaysia
, 2019 The Malaysia in space science R & D is still in its infancy stage. Internationally, space science has a major role and has impacted our society over the last 50 years and will continue providing returns on investment. The Return on Investment (ROI) could
Bahari, Siti Aminah +6 more
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