Results 131 to 140 of about 1,111,654 (254)

Spatially distributed complex organic matter detected in an ancient river valley in Jezero crater, Mars. [PDF]

Sci Adv
Murphy AE, Uckert K, Hand KP, Bhartia R, Bykov SV, Hickman-Lewis K, Jakubek RS, Lee C, McCubbin FM, Minitti ME, Pascuzzo A, Siljeström S, Sharma S, Steele A, Williford KH, Abbey W, Asher SA, Barnes R, Barr PA, Bell JF, Beyssac O, Bosak T, Bramble MS, Brown A, Broz AP, Buckner D, Cardarelli EL, Carsten JL, Corpolongo A, Czaja A, Edgington SGC, Ehlmann BL, Farley KA, Fornaro T, Fries M, González-Burgos R, Gupta S, Haney NC, Hug W, Huggett J, Hurowitz JA, Imbeah S, Clark J, Jones AJ, Kah LC, Kennedy MR, Lee SW, Maki J, Nixon B, Núñez JI, Osterhout JT, Phelan ND, Phua YY, Ravine MA, Hollis JR, Scheller E, Schulte MD, Sephton MA, Simon JI, Srivastava A, Stack KM, Van Beek J, Weiss BP, Wiens R, Williams AJ, Wogsland BV, Yingst RA.   +66 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

A Hybrid Inverse Kinematics Framework for Biomimetic Redundancy Resolution in 7-DoF Humanoid Arms. [PDF]

Biomimetics (Basel)
Shi Y, Chen Z, Mokiets I, Piao S, Zhang T, Zhang L.   +5 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Machine learning potentials for modeling alloys across compositions. [PDF]

Sci Adv
Sheriff K, Xiao DZ, Cao Y, Owen LR, Freitas R.   +4 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Programmable calculus operations in electromagnetic space using space-time-coding metasurface. [PDF]

Natl Sci Rev
Shi HT, Zhang L, Wu RY, Zheng YN, Chen XQ, Li Y, He S, Wu JW, Cheng Q, Cui TJ.   +9 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Ultra-narrowband perovskite single-crystal photodetector enabled by dynamic space charge region for portable concentration detection. [PDF]

Sci Adv
Hu G, Bian H, Luo D, Xia J, Wang L, Zhang J, Dai F, Xu X, Zhang L, Lin Q, Chen H, Jiang J, Hu W, Yao K, Shen L.   +14 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source