Results 111 to 120 of about 5,996,725 (288)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
National Space Science Data Center (NSSDC) Data Listing [PDF]
Satellite and nonsatellite data available from the National Space Science Data Center are listed. The Satellite Data listing includes the spacecraft name, launch date, and an alphabetical list of experiments.
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Space science and technologies to advance health-related sustainable development goals. [PDF]
Bull World Health Organ, 2018 Krishnamurthy RS, Hatton J.
europepmc +1 more source
Space Radiation and Impact on Instrumentation Technologies [PDF]
Understanding the interactions of the Sun, Earth and other natural and man-made objects in the solar system with the space radiation environment is crucial for improving activities of humans on Earth and in space.
Wrbanek, John D., Wrbanek, Susan Y.
core +1 more source
Editorial: Applications of statistical methods and machine learning in the space sciences
Frontiers in Astronomy and Space Sciences, 2023 Bala Poduval +4 more
doaj +1 more source