Results 101 to 110 of about 1,451,652 (301)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Space Science Institute: Curriculum Materials
Researchers and educators of the Space Science Institute are working together to "expand our knowledge of the space sciences and communicate that knowledge to the public." The Curriculum Materials page of the Web site contains three ...
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Regional Flooding Induced by Tide and Warm Water Effects in Tuvalu
Terrestrial, Atmospheric and Oceanic Sciences, 2015 A statistical model for simulating flood inundation in Tuvalu is developed in this study. The model is based on the major regional inundation factors - spring tides and warm-water mass, integrated with the digital elevation.
Chen-Chih Lin +3 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
The state of planetary science in Australia
, 2009 A head-count of Australia-based scientists doing research in planetary science was performed in the context of the drafting of the Decadal Plan for Space Sciences [1]. This paper builds on those findings.
Caprarelli, G
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
2012 Space Science Teacher's Summit
The Space Science Teachers Summit is a week-long professional development program for middle and high school teachers that brings the excitement of space science and exploration to students.
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Space for ambitions: the Dutch space program in changing European and transatlantic contexts
, 2014 Why would a small country like the Netherlands become active in space? The field was monopolized by large countries with large military establishments, especially in the early years of spaceflight.
Baneke, David +3 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source