Results 81 to 90 of about 1,451,652 (301)

Master of Science Space Systems Operations Brochure / 2012 [PDF]

open access: yes, 2012
The Master of Science in Space Systems Operations (MSSSO) Distributed Learning (DL) degree builds on 25 years experience educating military officers in masters and doctorate programs in space systems engineering and operations at the Naval ...
Tackett, Steve, Sands, Tim
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Artificial Intelligence: Societal and Ethical Implications Hearing before the Committee on Science, Space, and Technology House of Representatives

open access: yes, 2019
This report details a hearing by the Science, Space, and Technology Committee to discuss the impact of AI on society and the ethical implications in the design and use of this ...
United States. Congress. House. Committee on Science, Space, and Technology.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Trends in Space Astronomy and Cosmic Vision 2015-2025

open access: yes, 2005
To be published in the proceedings of the 2005 ESLAB Symposium "Trends in Space Science and Cosmic Vision 2020", held at ESTEC, 19-21 April 2005, F. Favata (ed).As a short introduction to the astronomy session, the response of the community to the Call ...
Henning, Thomas   +35 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Foresail-2: Space Physics Mission in a Challenging Environment [PDF]

open access: yes
Earth’s radiation belts are extremely important for space weather because they can store and accelerate particles to relativistic energies, which can have a potential impact on satellite functionality, communications, and navigation systems. The FORESAIL
Hiltunen Markus   +21 more
core   +1 more source

Virus Effect on Marine Synechococcus Spp. Loss in Subtropical Western Pacific Coastal Waters During Winter

open access: yesTerrestrial, Atmospheric and Oceanic Sciences, 2015
Little is known about microbial processes and the effect that viruses have on Synechococcus spp. in aquatic environments. This study investigated diel variations in the Synechococcus spp. abundance in three size-fractionated water samples (200, 10, and 2
An-Yi Tsai   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Slug Test in a Large Dip Angle Fracture Zone: Model and Field Experiment

open access: yesTerrestrial, Atmospheric and Oceanic Sciences, 2015
A single-porosity model is developed to deal with a fracture zone slug test in a large dip angle by assuming the fracture zone causes a downward regional flow.
Ying Liu and Chia-Shyun Chen
doaj   +1 more source

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