Results 71 to 80 of about 1,111,654 (254)
Slug Test in a Large Dip Angle Fracture Zone: Model and Field Experiment
Terrestrial, Atmospheric and Oceanic Sciences, 2015 A single-porosity model is developed to deal with a fracture zone slug test in a large dip angle by assuming the fracture zone causes a downward regional flow.
Ying Liu and Chia-Shyun Chen
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Abundant Landslides Associated with Extreme Weather Change During the 2009 Typhoon Morakot
Terrestrial, Atmospheric and Oceanic Sciences, 2015 The abundance of landslides that occurred in Taiwan in August of 2009 is not only attributed to extremely heavy rainfall but also extreme weather change from a dry period that occurred one month before the landslides to extremely heavy rainfall within a ...
Cheng-Horng Lin
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Space Science and Technology Education, Teaching, Research. [PDF]
Space Policy, 2020 Haubold HJ, Mathai AM, Pyenson L.
europepmc +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Terrestrial, Atmospheric and Oceanic Sciences, 2015 Accurate description of boundary layer processes is important for numerical simulations, and some model parameters in the boundary layer schemes play an important role in the model simulations.
Huiyan Xu +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source