Results 61 to 70 of about 31,547,886 (300)
Terrestrial, Atmospheric and Oceanic Sciences, 2015 The Chingshui geothermal area southwest of the Ilan plain is identified as a western extension of the Okinawa Trough in the northern Taiwan subduction system.
Chih-Wen Chiang +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Planetary science in Australia
, 2008 Planetary science studies the origin of the solar system and whether life exists on other planets. It has the potential to change the way we vie the world and our selves.
Walter, M +9 more
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Long-Term (1982 - 2012) Summertime Sea Surface Temperature Variability in the Taiwan Strait
Terrestrial, Atmospheric and Oceanic Sciences, 2015 Long-term (1982 - 2012) advanced very-high-resolution radiometer (AVHRR) data collected at a resolution of 0.04°0.04° clearly indicated sea surface temperature (SST) warming and variations associated with El NiñoNiño and Southern Oscillation (ENSO) in ...
Ming-An Lee +4 more
doaj +1 more source
Space science is alive with art
, 2013 The history of human space flight and analogue and ground-based space science is alive with art. Artists, scientists and engineers working together build upon diverse frameworks of understanding, but also share tools and processes of investigation.
Pell, Sarah Jane (author) +3 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source