Results 41 to 50 of about 1,111,654 (254)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Long-Term (1982 - 2012) Summertime Sea Surface Temperature Variability in the Taiwan Strait

open access: yesTerrestrial, Atmospheric and Oceanic Sciences, 2015
Long-term (1982 - 2012) advanced very-high-resolution radiometer (AVHRR) data collected at a resolution of 0.04°0.04° clearly indicated sea surface temperature (SST) warming and variations associated with El NiñoNiño and Southern Oscillation (ENSO) in ...
Ming-An Lee   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Using Electrodynamic Tethers to Create Artificial Sun-Synchronous Orbits and De-Orbit Remote Sensing Satellites

open access: yesUniverse
This paper has the goal of exploring the potential of electromagnetic propulsion systems based on tethers to create artificial Sun-synchronous orbits for remote sensing satellites, as well as performing station-keeping maneuvers and de-orbiting of the ...
Antonio F. B. A. Prado   +1 more
doaj   +1 more source

Hot Spring Gas Geochemistry in Western Sichuan Province, China After the Wenchuan Ms 8.0 Earthquake

open access: yesTerrestrial, Atmospheric and Oceanic Sciences, 2015
The chemical components, He, Ne, and C isotropic ratios of gas samples collected thrice from 32 hot springs in western Sichuan Province, southwestern China in June and October 2008 and June 2009 were investigated in order to discuss the relationship ...
Xiaocheng Zhou   +9 more
doaj   +1 more source

Guest Editorial: International Space Science Institute (ISSI) Workshop on Global Change in Africa. [PDF]

open access: yesSurv Geophys, 2023
Cazenave A   +5 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Home - About - Disclaimer - Privacy