Results 41 to 50 of about 1,451,652 (301)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Terrestrial, Atmospheric and Oceanic Sciences, 2015 Espichel-Sines is an embayed coast in SW Portugal, consisting of two capes at both extremities, a tidal inlet and associated ebb tidal delta, a barrier spit, sandy beaches, sea cliffs, and a submarine canyon.
Xiaoqin Du +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Organizing space: Dutch space science between astronomy, industry and the government
, 2016 This paper analyzes how scientists, private companies and the government in the Netherlands cooperated in the creation of the new field of space research. It examines especially the role of Philips Electronics and Fokker Aircraft, and the consequences of
Sub History and Philosophy of Science +5 more
core +1 more source
One-Dimensional Velocity Structure of the Crust in Fujian, Southeast China
Terrestrial, Atmospheric and Oceanic Sciences, 2015 12095 P-wave phase data were selected in this study from four NW-oriented and four NE-oriented explosion sounding survey lines conducted along the coast and midland of Southeast China during the years 2010 and 2012.
Hui-Teng Cai +2 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Exoplanet science with a space-based mid-infrared nulling interferometer [PDF]
, 2018 One of the long-term goals of exoplanet science is the (atmospheric) characterization of a large sample (>100) of terrestrial planets to assess their potential habitability and overall diversity.
Glauser, A. M. +16 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Space Universities Network-Supporting space science and engineering higher education community in the UK [PDF]
, 2018 The world space economy is expected to grow to $400 billion by 2030 and to provide 100,000 jobs. In the UK we currently have 38,500 directly employed with a further 70000 jobs dependent on the space sector.
Bannister, Nigel +36 more
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