Results 51 to 60 of about 1,451,652 (301)

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Achievements and Challenges in the Science of Space Weather [PDF]

, 2017
In June 2016 a group of 40 space weather scientists attended the workshop on Scientific Foundations of Space Weather at the International Space Science Institute in Bern.
Rudolf von Steiger, Baker, Daniel N., Balogh, André, Astrid Veronig, Gombosi, Tamas, André Balogh, von Steiger, Rudolph, Hannu E. J. Koskinen, Koskinen, Hannu E. J., Veronig, Astrid, Tamas Gombosi, Daniel N. Baker   +11 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

SWIFF : space weather integrated forecasting framework [PDF]

, 2013
This research has received funding from the European Commission’s FP7 Program with the grant agreement SWIFF (Project No. 2633430, swiff.eu). The KU Leuven simulations were conducted on the computational resources provided by the PRACE Tier-0 Project No.
Viviane Pierrard, Bemporad, Alessandro, Parnell, Clare Elizabeth, O. Sebek, HENRI, PIERRE REMI ANTOINE, Mackay, Duncan H., Ondřej Šebek, Clare E. Parnell, Nordlund, Åke, Trávníček, Pavel M., Bemporad, A., Åke Nordlund, Mackay, Duncan Hendry, R. Keppens, A. Restante, Alessandro Bemporad, Pegoraro, Francesco, Parnell, C., V. Pierrard, Pierrard, Viviane, Markidis, Stefano,, D. Mackay, Keppens, R., Restante, A., Mackay, D., Faganello, Matteo, Stefano Markidis, Jacob Trier Frederiksen, Mackay, D.H., A. Bemporad, Faganello, M., Rony Keppens, Kris Borremans, Olshevsky, Vyacheslav, Pegoraro, F., Susino, R., M. Faganello V. Olshevsky, Parnell, Clare E., Borremans, K., K. Borremans, S. Poedts, Parnell, C.E., C. Parnell, Frederiksen, J., Lapenta, G., Califano, Francesco, S. Markidis, Francesco Califano, Restante, A.L., Borremans, Kris, Giovanni Lapenta, Pierrard, V., Keppens, Rony, Šebek, Ondřej, Trier Frederiksen, Jacob, Susino, Roberto, Lapenta, Giovanni, Henri, P., Califano, F., J. Frederiksen, Pavel M. Trávníček, Travnıcek, P., Pierre Henri, Restante, Anna Lisa, Markidis, S., Henri, Pierre, Stefaan Poedts, Vyacheslav Olshevsky, Markidis, Stefano, Duncan H. Mackay, Poedts, S., R. Susino, Frederiksen, Jacob Trier, Nordlund, A., G. Lapenta, Sebek, O., Anna Lisa Restante, Trávníček, P.M., Roberto Susino, Poedts, Stefaan, Olshevsky, V., A. Nordlund, Matteo Faganello, Francesco Pegoraro, Trávníček, Pavel M   +84 more
core   +1 more source

b-Values Observations in Taiwan: A Review

Terrestrial, Atmospheric and Oceanic Sciences, 2015
High seismicity with spatial heterogeneity in Taiwan makes this region one of the best natural laboratories for seismological researches. Numerous seismicity studies, including the b-value, have been performed for more than one century.
Jeen-Hwa Wang, Kou-Cheng Chen, Pei-Ling Leu, and Jeng-Hsin Chang   +3 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source